Flexibility and Structure of Fluid Bilayer Interfaces

Rappolt, Michael; Pabst, Georg

doi:10.1002/9780470388495.ch3

Cited by 17 publications

(21 citation statements)

References 113 publications

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“…1 here. POPC bilayers alone have been thoroughly studied and analysed, both under constant temperature and rapid heating conditions (Pabst et al, 2000a;Pabst et al, 2000b;Rappolt et al, 2004;Rappolt and Pabst, 2008). The displayed structural behavior in the temperature range from 15 to 65°C compares well to literature results (Fig.…”

Section: Structural Changes In the Bilayersupporting

confidence: 68%

“…Background corrected SAXS patterns were analysed by the application of the modified Caillé theory (see Supplementary material). The technique and underlying premises have been described previously in detail (Pabst et al, 2003;Pabst et al, 2000b; for a review see Rappolt and Pabst, 2008)). The bilayer model used and its applications have been presented elsewhere (Rappolt, 2010).…”

Section: Small Angle X-ray Scattering Experimentsmentioning

confidence: 99%

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Fullerene up-take alters bilayer structure and elasticity: A small angle X-ray study

Drašler

Drobne

Sadeghpour

et al. 2015

Chemistry and Physics of Lipids

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The coupling of fullerene (C 60 ) to the structure and elasticity of 1-palmitoyl-2-oleoyl-snglycero-3-phosphocholine bilayers has been explored by synchrotron small angle X-ray scattering. Multilamellar vesicles were loaded with 0, 2 and 10 mol. % of C 60 and studied in a temperature range from 15-65°C. The addition of C 60 caused an increase in the bilayer undulations (~20 %), in the bilayer separation (~15%), in the linear expansion coefficient and caused a drop in the bending rigidity of the bilayers (20-40 %). Possible damaging effects of fullerene on biomembranes are mainly discussed on the basis of altered bilayer fluidity and elasticity changes.

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Section: Structural Changes In the Bilayersupporting

confidence: 68%

Section: Small Angle X-ray Scattering Experimentsmentioning

confidence: 99%

Fullerene up-take alters bilayer structure and elasticity: A small angle X-ray study

Drašler

Drobne

Sadeghpour

et al. 2015

Chemistry and Physics of Lipids

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“…A Mythen X ray detector (Dectris Ltd, Baden, Switzerland) 18 system was used to record the 1D scattering patterns. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 described previously in depth 27,28 − for reviews see Rappolt et al 29 and Pabst et al 30 The bilayer 1 model used to interpret the data and its applications have also been described previously. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 ...…”

Section: Films 10mentioning

confidence: 94%

Experimental Modeling of Flavonoid–Biomembrane Interactions

Sanver

Murray²,

Sadeghpour³

et al. 2016

Langmuir

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and visualization of the surface with BAM revealed a pronounced monolayer stabilization effect 10 with both quercetin and tiliroside, whereas rutin disrupted the monolayer structure rendering the 11 surface entirely smooth. SAXS showed a monotonous membrane thinning for all compounds 12 studied associated with an increase in the root mean square fluctuations of the membrane. Rutin, 13 quercetin and tiliroside decreased the bilayer thickness of DOPC by ~0.45 Å, 0.8 Å, and 1.1 Å at 14 6 mol %, respectively. In addition to the novelty of using lipid monolayers to systematically 15 characterize the structure activity relationship (SAR) of a variety of flavonoids; this is the first 16 report investigating the effect of tiliroside with biomimetic membrane models. All the flavonoids 17 studied are believed to be localized in the lipid/water interface region. Both this localization and 18 the membrane perturbations have implications for their therapeutic activity.

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“…[91] for a comprehensive review). However, to the best of the author's knowledge, there is only one method, which is capable of deriving the bending rigidity of lipid domains.…”

Section: Bending Rigiditymentioning

confidence: 99%