Flexible, label free and low-cost paper based microfluidic SERS substrates for thiram detection

Naqvi, Tania K.; Bajpai, Abhilash; Dwivedi, Sarthak; Bhaiyya, Manish; Goel, Sanket; Dwivedi, Prabhat K.

doi:10.1016/j.sna.2023.114341

Cited by 14 publications

(3 citation statements)

References 51 publications

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“…Wax printing is a simple technique, as shown in the example in Figure 3B. 59 to polymer-based methods. 60 Additionally, they lack the ability to perform complex mixing or sample digitization processes offered by polymer-based methods.…”

Section: Papermentioning

confidence: 99%

Section: Microfluidic Chip Materials and Manufacturingmentioning

confidence: 99%

“…Wax printing is a simple technique, as shown in the example in Figure 3B . 59 For this µPAD, Whatman filter paper was first cut into the desired dimensions and then dipped into a wax solution. Various wax laminated paper moulds were then generated from CO 2 lasering to create prepared masks.…”

Section: Microfluidic Chip Materials and Manufacturingmentioning

confidence: 99%

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Ensuring food safety: Microfluidic‐based approaches for the detection of food contaminants

Kasputis,

Hosmer,

et al. 2024

Analytical Science Advances

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Detecting foodborne contamination is a critical challenge in ensuring food safety and preventing human suffering and economic losses. Contaminated food, comprising biological agents (e.g. bacteria, viruses and fungi) and chemicals (e.g. toxins, allergens, antibiotics and heavy metals), poses significant risks to public health. Microfluidic technology has emerged as a transformative solution, revolutionizing the detection of contaminants with precise and efficient methodologies. By manipulating minute volumes of fluid on miniaturized systems, microfluidics enables the creation of portable chips for biosensing applications. Advancements from early glass and silicon devices to modern polymers and cellulose‐based chips have significantly enhanced microfluidic technology, offering adaptability, flexibility, cost‐effectiveness and biocompatibility. Microfluidic systems integrate seamlessly with various biosensing reactions, facilitating nucleic acid amplification, target analyte recognition and accurate signal readouts. As research progresses, microfluidic technology is poised to play a pivotal role in addressing evolving challenges in the detection of foodborne contaminants. In this short review, we delve into various manufacturing materials for state‐of‐the‐art microfluidic devices, including inorganics, elastomers, thermoplastics and paper. Additionally, we examine several applications where microfluidic technology offers unique advantages in the detection of food contaminants, including bacteria, viruses, fungi, allergens and more. This review underscores the significant advancement of microfluidic technology and its pivotal role in advancing the detection and mitigation of foodborne contaminants.

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Section: Papermentioning

confidence: 99%

Section: Microfluidic Chip Materials and Manufacturingmentioning

confidence: 99%

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Ensuring food safety: Microfluidic‐based approaches for the detection of food contaminants

Kasputis,

Hosmer,

et al. 2024

Analytical Science Advances

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Asymmetrical Absorption and Surface‐Enhanced Raman Scattering Enhancement by Silver Nanoflower Metasurface

Jen,

Wang,

Zhan

et al. 2024

Advanced Photonics Research

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A metasurface composed of silver nanoflower arrays, which exhibit asymmetrical absorption and surface‐enhanced Raman scattering (SERS) due to hybrid plasmonic effects, is reported. The silver nanoflowers are fabricated by oblique deposition of silver on a polymer nanohole array on a glass substrate, forming petal‐like semicontinuous thin films on the inner walls of the holes. Depending on the deposition angle, three‐ or five‐petal nanoflowers are obtained. The nanoflower arrays show strong reflection from the air side and broadband and wide‐angle absorption from the glass side, as a result of transmission surface plasmon resonance and localized surface plasmon resonance, respectively. The three‐petal structure, which absorbs most of the incident light from the glass side, induces a localized enhancement of electric field in the center of each nanohole, providing a high‐sensitivity SERS substrate. The SERS performance of the metasurface by direct measurement and near‐field simulation is demonstrated.

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Effect of pH on the optimization of cysteine‐functionalized gold core‐silver shell nanoparticles for surface‐enhanced Raman scattering‐based pesticide detection on apple peels

Dayalan

Sudewi

Zulfajri

et al. 2023

J Chinese Chemical Soc

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BackgroundThe rapid detection and efficient properties of surface‐enhanced Raman scattering (SERS) have been widely exploited in food safety.PurposeIn this study, the SERS impact of cysteine‐functionalized gold core‐silver shell bimetallic nanoparticle (Au@Ag@CysNPs) substrates with different pH treatments on pesticide compounds was examined.ResultsThe pH‐dependent SERS impact of Au@Ag@CysNPs on detecting pesticide compounds exhibited different enhancements over the pH range of 2–11 and exited the highest enhancement at a pH of 5 for thiabendazole and thiram pesticides. The prepared Au@Ag@CysNPs were further utilized in SERS‐based rapid detection of pesticides on apple peels by directly dropping Au@Ag@CysNPs on the surface of the samples, where the target molecules could be identified without elution or extraction. These findings revealed that this Au@Ag@CysNPs substrate exhibited excellent SERS performances for pesticide compounds and good stability. With additional optimization, detection limits of 0.1 ng/cm2 for thiabendazole and thiram on apple peels were obtained.

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Flexible, label free and low-cost paper based microfluidic SERS substrates for thiram detection

Cited by 14 publications

References 51 publications

Ensuring food safety: Microfluidic‐based approaches for the detection of food contaminants

Ensuring food safety: Microfluidic‐based approaches for the detection of food contaminants

Asymmetrical Absorption and Surface‐Enhanced Raman Scattering Enhancement by Silver Nanoflower Metasurface

Effect of pH on the optimization of cysteine‐functionalized gold core‐silver shell nanoparticles for surface‐enhanced Raman scattering‐based pesticide detection on apple peels

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