Flexible paper-based Ni-MOF composite/AuNPs/CNTs film electrode for HIV DNA detection

Lu, Qin; Song, Tong; Shang, Zhenjiao; Jin, Dayong; Shu, Yun; Xu, Qin

doi:10.1016/j.bios.2021.113229

Cited by 96 publications

(34 citation statements)

References 49 publications

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“…As of November 2021, the number of reported infections worldwide has exceeded 252 million ( World Health Organization, 2021 ), causing severe harm to human health and the global economy. MOF-based electrochemical sensors have been proposed for detecting viruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ( El-Sherif et al, 2021 ), human immunodeficiency virus (HIV) ( Lu et al, 2021 ), hepatitis-C virus (HCV) ( Sheta et al, 2020 ), which are essential for diagnostic treatment and delaying the spread of diseases.…”

Section: Introductionmentioning

confidence: 99%

Recent Advances in Metal-Organic Framework-Based Electrochemical Biosensing Applications

Li¹,

Zhang²,

Boakye³

et al. 2021

Front. Bioeng. Biotechnol.

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In the face of complex environments, considerable effort has been made to accomplish sensitive, accurate and highly-effective detection of target analytes. Given the versatility of metal clusters and ligands, high porosity and large specific surface area, metal–organic framework (MOF) provides researchers with prospective solutions for the construction of biosensing platforms. Combined with the benefits of electrochemistry method such as fast response, low cost and simple operation, the untapped applications of MOF for biosensors are worthy to be exploited. Therefore, this review briefly summarizes the preparation methods of electroactive MOF, including synthesize with electroactive ligands/metal ions, functionalization of MOF with biomolecules and modification for MOF composites. Moreover, recent biosensing applications are highlighted in terms of small biomolecules, biomacromolecules, and pathogenic cells. We conclude with a discussion of future challenges and prospects in the field. It aims to offer researchers inspiration to address the issues appropriately in further investigations.

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Section: Introductionmentioning

confidence: 99%

Recent Advances in Metal-Organic Framework-Based Electrochemical Biosensing Applications

Li¹,

Zhang²,

Boakye³

et al. 2021

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

show abstract

“…In Li’s review [ 63 ], they introduced the types of neurotransmitters and biological sample sources which were used for neurotransmitter detection and then reviewed the traditional fabrication technologies and modification methods for paper-based electrochemical POCT devices. In Lu’s work [ 64 ], ePad was used for human immunodeficiency virus (HIV) DNA detection with methylene blue (MB) as a redox indicator. A paper-based electrode was made by using nickel metal–organic framework (Ni-MOF) composite/Au nanoparticles/carbon nanotubes/polyvinyl alcohol (Ni–Au composite/CNT/PVA).…”

Section: Electrochemical Detection Methodsmentioning

confidence: 99%

Recent Advances and Applications in Paper-Based Devices for Point-of-Care Testing

Hou

Guo

et al. 2022

J. Anal. Test.

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Point-of-care testing (POCT), as a portable and user-friendly technology, can obtain accurate test results immediately at the sampling point. Nowadays, microfluidic paper-based analysis devices (μPads) have attracted the eye of the public and accelerated the development of POCT. A variety of detection methods are combined with μPads to realize precise, rapid and sensitive POCT. This article mainly introduced the development of electrochemistry and optical detection methods on μPads for POCT and their applications on disease analysis, environmental monitoring and food control in the past 5 years. Finally, the challenges and future development prospects of μPads for POCT were discussed.

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“…Therefore, the proper design and preparation of composites is necessary to obtain enhanced conductivity. Lu et al developed a paper-based nickel metal-organic framework (Ni-MOF) composite/Au nanoparticles/carbon nanotubes/polyvinyl alcohol (Ni-Au composite/CNT/PVA) film electrode for HIV DNA detection [ 177 ]. A mixture of CNT and PVA was deposited on a cellulose membrane by vacuum filtration to fabricate the working electrode.…”

Section: Recent Applications Of Paper-based Analytical Devices For Virus Detectionmentioning

confidence: 99%

Paper-based analytical devices for virus detection: Recent strategies for current and future pandemics

Özer

Henry

2021

TrAC Trends in Analytical Chemistry

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The importance of user-friendly, inexpensive, sensitive, and selective detection of viruses has been highlighted again due to the recent Coronavirus disease 2019 (COVID-19) pandemic. Among the analytical tools, paper-based devices (PADs) have become a leading alternative for point-of-care (POC) testing. In this review, we discuss the recent development strategies and applications in nucleic acid-based, antibody/antigen-based and other affinity-based PADs using optical and electrochemical detection methods for sensing viruses. In addition, advantages and drawbacks of presented PADs are identified. Current state and insights towards future perspectives are presented regarding developing POC diagnosis platform for COVID-19. This review considers state-of-the-art technologies for further development and improvement in PADs performance for virus detection.

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Flexible paper-based Ni-MOF composite/AuNPs/CNTs film electrode for HIV DNA detection

Cited by 96 publications

References 49 publications

Recent Advances in Metal-Organic Framework-Based Electrochemical Biosensing Applications

Recent Advances in Metal-Organic Framework-Based Electrochemical Biosensing Applications

Recent Advances and Applications in Paper-Based Devices for Point-of-Care Testing

Paper-based analytical devices for virus detection: Recent strategies for current and future pandemics

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