Flexible screen printed biosensor with high-Q microwave resonator for rapid and sensitive detection of glucose

Adhikari, Kishor Kumar; Chuluunbaatar, Zorigt; Park, Hyejin; Jung, Younsu; Cho, Gyoujin; Jo, Yunhee; Kim, Sung Soo; Kim, Nam Young

doi:10.1109/imws-bio.2014.7032431

Cited by 13 publications

(10 citation statements)

References 6 publications

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“… Proposed flexible glucose biosensor: ( a ) 3D layout of the resonator fabricated on a PET substrate; ( b ) schematic view of the sensing region of the resonator with a glucose–water solution; ( c ) simulated and measured S 11 , including a photograph of the fabricated resonator; and ( d ) the equivalent circuit of the proposed biosensing resonator [ 94 ]. …”

Section: Figurementioning

confidence: 99%

“… Detection of glucose level using measured S-parameters: ( a ) shift of central frequency; ( b ) linearly fitted central frequency and actual central frequency with error bar; and ( c ) variation of loaded quality factor ( Q L ) and return loss ( S 11 ) with variation in glucose concentration [ 94 ]. …”

Section: Figurementioning

confidence: 99%

“… Detection of glucose level using derived parameters: ( a ) propagation constant ( γ ); and ( b ) impedance ( Z ) [ 94 ]. …”

Section: Figurementioning

confidence: 99%

See 2 more Smart Citations

Review of Batteryless Wireless Sensors Using Additively Manufactured Microwave Resonators

Memon

Lim

2017

Sensors

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The significant improvements observed in the field of bulk-production of printed microchip technologies in the past decade have allowed the fabrication of microchip printing on numerous materials including organic and flexible substrates. Printed sensors and electronics are of significant interest owing to the fast and low-cost fabrication techniques used in their fabrication. The increasing amount of research and deployment of specially printed electronic sensors in a number of applications demonstrates the immense attention paid by researchers to this topic in the pursuit of achieving wider-scale electronics on different dielectric materials. Although there are many traditional methods for fabricating radio frequency (RF) components, they are time-consuming, expensive, complicated, and require more power for operation than additive fabrication methods. This paper serves as a summary/review of improvements made to the additive printing technologies. The article focuses on three recently developed printing methods for the fabrication of wireless sensors operating at microwave frequencies. The fabrication methods discussed include inkjet printing, three-dimensional (3D) printing, and screen printing.

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Section: Figurementioning

confidence: 99%

Section: Figurementioning

confidence: 99%

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Review of Batteryless Wireless Sensors Using Additively Manufactured Microwave Resonators

Memon

Lim

2017

Sensors

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“…Due to their great sensitivity, fast response times, resilience, reusability, and cost-effectiveness, microwave resonators are widely used in sensing systems as well as RF/microwave communication systems [ 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 ]. Common microwave technologies used in sensing systems include parallel plate capacitors, microstrip lines, and cavity resonators [ 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 42 , 45 , 46 ].…”

Section: Introductionmentioning

confidence: 99%

A Multilayered GaAs IPD Resonator with Five Airbridges for Sensor System Application

Zhang,

Wang,

Chen

et al. 2024

Micromachines

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This work proposes a microwave resonator built from gallium arsenide using integrated passive device (IPD) technology. It consists of a three-layered interlaced spiral structure with airbridges and inner interdigital structures. For integrated systems, IPD technology demonstrated outstanding performance, robustness, and a tiny size at a low cost. The airbridges were made more compact, with overall dimensions of 1590 × 800 µm2 (0.038 × 0.019 λg2). The designed microwave resonator operated at 1.99 GHz with a return loss of 39 dB, an insertion loss of 0.07 dB, and a quality factor of 1.15. Additionally, an experiment was conducted on the properties of the airbridge and how they affected resistance, inductance, and S-parameters in the construction of the resonator. To investigate the impact of airbridges on the structure, E- and H-field distributions of the resonator were simulated. Furthermore, its use in sensing applications was explored. Various concentrations of glucose solutions were used in the experiment. The proposed device featured a minimum detectable concentration of 0.2 mg/mL; high sensitivity, namely, 14.58 MHz/mg·mL−1, with a linear response; and a short response time. Thus, this work proposes a structure that exhibits potential in integrated systems and real-time sensing systems with high sensitivity.

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“…The previous studies reveal that the product of the filling factor and loaded quality(Q)-factor is essential to get high sensitivity [ 31 , 32 ]. Several resonators with high Q-value measurements have been demonstrated for glucose-sensing applications [ 33 , 34 ]. The high value of the loaded Q-factor enhances the localized electric field intensity that increases sensitivity.…”

Section: Introductionmentioning

confidence: 99%

High-Sensitivity, Quantified, Linear and Mediator-Free Resonator-Based Microwave Biosensor for Glucose Detection

Kumar

Wang

Meng

et al. 2020

Sensors

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This article presents a high-sensitivity, quantified, linear, and mediator-free resonator-based microwave biosensor for glucose sensing application. The proposed biosensor comprises an air-bridge-type asymmetrical differential inductor (L) and a center-loaded circular finger-based inter-digital capacitor (C) fabricated on Gallium Arsenide (GaAs) substrate using advanced micro-fabrication technology. The intertwined asymmetrical differential inductor is used to achieve a high inductance value with a suitable Q-factor, and the centralized inter-digital capacitor is introduced to generate an intensified electric field. The designed microwave sensor is optimized to operate at a low resonating frequency that increases the electric field penetration depth and interaction area in the glucose sample. The microwave biosensor is tested with different glucose concentrations (0.3–5 mg/ml), under different ambient temperatures (10–50 °C). The involvement of advanced micro-fabrication technology effectively miniaturized the microwave biosensor (0.006λ0 × 0.005λ0) and enhanced its filling factor. The proposed microwave biosensor demonstrates a high sensitivity of 117.5 MHz/mgmL-1 with a linear response (r2 = 0.9987), good amplitude variation of 0.49 dB/mgmL-1 with a linear response (r2 = 0.9954), and maximum reproducibility of 0.78% at 2 mg/mL. Additionally, mathematical modelling was performed to estimate the dielectric value of the frequency-dependent glucose sample. The measured and analyzed results indicate that the proposed biosensor is suitable for real-time blood glucose detection measurements.

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Flexible screen printed biosensor with high-Q microwave resonator for rapid and sensitive detection of glucose

Cited by 13 publications

References 6 publications

Review of Batteryless Wireless Sensors Using Additively Manufactured Microwave Resonators

Review of Batteryless Wireless Sensors Using Additively Manufactured Microwave Resonators

A Multilayered GaAs IPD Resonator with Five Airbridges for Sensor System Application

High-Sensitivity, Quantified, Linear and Mediator-Free Resonator-Based Microwave Biosensor for Glucose Detection

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