Flexor tendon healing and adhesion formation after Sterispon wrapping: a study in the rabbit

Austin, R.T.; Walker, F. G.

doi:10.1016/0020-1383(79)90011-1

Cited by 17 publications

(5 citation statements)

References 12 publications

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“…Adhesion barriers refer to physical or chemical barriers that are applied to the tendon in an attempt to minimize adhesion formation. Numerous physical barriers to adhesion formation have been studied, including the application of silicone, polyethylene membranes, alumina shields, polytetrafluoroethylene, and polyhydroxyethylmethylmethacrylate membranes . None of these have been successful enough to be used clinically.…”

Section: Surface Modification/adhesion Barriersmentioning

confidence: 99%

Advances in the healing of flexor tendon injuries

Sammer

Chung

2014

Wound Repair Regeneration

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The intrasynovial flexor tendons of the hand are critical for normal hand function. Injury to these tendons can result in absent finger flexion, and a subsequent loss of overall hand function. The surgical techniques used to repair these tendons have improved in the past few decades, as have the postoperative rehabilitation protocols. In spite of these advances, intrasynovial flexor tendon repairs continue to be plagued by postoperative scar formation, which limits tendon gliding and prevents a full functional recovery. This paper describes the current challenges of flexor tendon repair, and evaluates the most recent advances and strategies for achieving an excellent functional outcome.

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Section: Surface Modification/adhesion Barriersmentioning

confidence: 99%

Advances in the healing of flexor tendon injuries

Sammer

Chung

2014

Wound Repair Regeneration

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“…Some researchers have focused on creating a barrier between the healing tendon and its sheath to reduce the effects of extrinsic healing. Various materials have been tried including alumina sheaths, 13 silicone, 14 and polyethylene membranes 15 among many others. None are in routine use clinically.…”

Section: Molecular Basis Of Flexor Tendon Wound Healingmentioning

confidence: 99%

Clinical implications of growth factors in flexor tendon wound healing

Hsu

Chang

2004

The Journal of Hand Surgery

147

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“…Modification of the adhesion process by various biochemical agents has been attempted, both by placing a mechanical barrier between the healing tendon and the surrounding tissue and by chemically modulating the actual formation of adhesions. The physical barriers to adhesions have included polyethylene membranes, alumina sheaths, polytetrafluoroethylene and chondroitin sulphate-coated polyhydroxyethyl methacrylate membranes and, most recently, ADCON®, a proteoglycan (Austin and Walker, 1979; Eskeland et al, 1977; Golash et al, 2002; Gudemez et al, 2002; Hanff and Hagberg, 1998; Siddiqi et al, 1995). Biochemical modulation of the adhesion process has also been studied extensively in both extrasynovial and intrasynovial tendons.…”

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confidence: 99%

The Effect of Thermal Preconditioning of the Limb on Flexor Tendon Healing

Healy

Mulhall

Patrick

et al. 2007

J Hand Surg Eur Vol

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Thermal preconditioning reduces inflammation by inducing cytoprotective heat shock proteins. We evaluated the role of limb thermal preconditioning in a rabbit model of flexor tendon repair. The treatment groups underwent limb preconditioning by elevating the limb temperature to 41.5 1C for 20 minutes. The animals were sacrificed three and six weeks after flexor tendon repair. Heat shock protein72 expression of the treated limb was measured at 18 hours. Macroscopic analysis demonstrated a significant decrease in adhesion formation in the three week treatment group. The inflammatory infiltrate was significantly reduced for both treatment groups. The difference in ultimate tensile strength was not significant. We conclude that thermal preconditioning of the limb before flexor tendon repair decreases inflammation and adhesion formation in a rabbit model and has the potential to improve clinical outcome of flexor tendon surgery.

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Flexor tendon healing and adhesion formation after Sterispon wrapping: a study in the rabbit

Cited by 17 publications

References 12 publications

Advances in the healing of flexor tendon injuries

Advances in the healing of flexor tendon injuries

Clinical implications of growth factors in flexor tendon wound healing

The Effect of Thermal Preconditioning of the Limb on Flexor Tendon Healing

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