Floating electrode optoelectronic tweezers: Light-driven dielectrophoretic droplet manipulation in electrically insulating oil medium

Park, Sung-Yong; Pan, Chenlu; Wu, Ting-Hsiang; Kloss, Christoph; Kalim, Sheraz; Callahan, Caitlin; Teitell, Michael A.; Chiou, Eric P. Y.

doi:10.1063/1.2906362

Cited by 56 publications

(32 citation statements)

References 16 publications

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“…Park's group achieved droplet manipulation in oil using a sandwiched OET platform integrated with microfluidic channels and showed the manipulation of picoliter droplets by optically induced DEP forces [63]. Park et al have recently demonstrated a mechanism, called floating electrode optoelectronic tweezers (FEOET), specifically aiming for manipulating aqueous droplets suspended in electrically insulating oil and air media ( Figure 9) [64]. FEOET utilizes lateral electric field as in SCOEW.…”

Section: Optoelectronic Tweezers (Oet)mentioning

confidence: 99%

Light-Driven Droplet Manipulation Technologies for Lab-on-a-Chip Applications

Park

Chiou

2011

Advances in OptoElectronics

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Droplet-based (digital) microfluidics has been demonstrated in many lab-on-a-chip applications due to its free crosscontamination and no dispersion nature. Droplet manipulation mechanisms are versatile, and each has unique advantages and limitations. Recently, the idea of manipulating droplets with light beams either through optical forces or light-induced physical mechanisms has attracted some interests, since light can achieve 3D addressing, carry high energy density for high speed actuation, and be patterned and dynamically reconfigured to generate a large number of light beams for massively parallel manipulation. This paper reviews recent developments of various optical technologies for droplet manipulation and their applications in lab-on-achip.

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Section: Optoelectronic Tweezers (Oet)mentioning

confidence: 99%

Light-Driven Droplet Manipulation Technologies for Lab-on-a-Chip Applications

Park

Chiou

2011

Advances in OptoElectronics

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“…In order to solve this problem, a threedimensional (3D) OEK chip consisting of two parallel photosensitive layers was designed to set up a symmetrical spatial electric field and focus the object in the middle of the liquid layer [70]. A single-sided ODEP device was also developed to enable manipulation based on a modulation of lateral electric field generated by the interdigitated electrodes patterned on a single-side substrate [61] or a floating electrode [65,71].…”

Section: Q4mentioning

confidence: 99%

Micro and Nano Manipulation and Assembly by Optically Induced Electrokinetics

Lai

et al. 2015

Micro‐ and Nanomanipulation Tools

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IntroductionIn the past 25 years, integrated circuit (IC) and microelectromechanical systems (MEMSs) technologies have moved much beyond the microdomain, and into the submicro-, nanoscopic, and, even, the molecular scales. Today, we have the capability to fabricate, manipulate, and assemble matters at the micro-, nano-, or molecular scales. This progress into "seeing" and manipulating matters that are smaller than visible light wavelength scale is impacting a range of fields including semiconductor physics, biological studies, pharmaceutical development, and many other scientific and technological applications. A range of new methods to generate physical forces have been developed in the process. For example, mechanical forces can now be applied to micro-, nano-, and biological entities using atomic force microscope probes [1], microgrippers [2], or pipettes [3]. However, disadvantages of these approaches, including inflection of mechanical damages on objects being manipulated and their relatively low manipulation speed, make manipulation of large quantities of objects difficult. In order to address these disadvantages, noncontact or noninvasive methods for micro-, nano-, and biological manipulation have also been explored in the past two decades.Manipulation devices based on magnetic forces [4], acoustic waves [5,6], hydrodynamic flows [7], light waves [8], or electrokinetic forces [9] are among the major noninvasive technologies available today. Each of them has its own advantages and disadvantages. Methods based on magnetic fields need premodification on objects with magnetic beads which constrains their application domain. In addition, movement controlled by permanent magnets is not precise enough for many proposed applications. Also, the high resistance of the magnetic coil generates significant heat during manipulation [10]. Acoustic traps show good selectivity but cannot achieve parallel manipulation of single entities. Microfluidic devices exploiting hydrodynamic flows are suitable for cell population sorting, but have difficulties in trapping or controlling specific single objects.Electrokinetic forces generated from patterned electrodes capable of inducing the desired spatial distribution of electric field have been exploited to control

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“…Similar to the concept of OET, floating electrode optoelectronic tweezers (FEOET) explores another frequency regime for aqueous droplet manipulation 103,104 ( Fig. 9d).…”

Section: Floating Electrode Optoelectronic Tweezers (Feoet)mentioning

confidence: 99%

“…9d). Park et al 103,104 showed that a target object as large as a nano-litre droplet in a two-phase environment, such as water in oil, can be driven by a light-induced dipole moment. The electric field is created by a DC bias on two far separated electrodes.…”

Section: Floating Electrode Optoelectronic Tweezers (Feoet)mentioning

confidence: 99%

Hybrid opto-electric manipulation in microfluidics—opportunities and challenges

et al. 2011

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Hybrid opto-electric manipulation in microfluidics/nanofluidics refers to a set of methodologies employing optical modulation of electrokinetic schemes to achieve particle or fluid manipulation at the micro-and nano-scale. Over the last decade, a set of methodologies, which differ in their modulation strategy and/or the length scale of operation, have emerged. These techniques offer new opportunities with their dynamic nature, and their ability for parallel operation has created novel applications and devices. Hybrid opto-electric techniques have been utilized to manipulate objects ranging in diversity from millimetre-sized droplets to nano-particles. This review article discusses the underlying principles, applications and future perspectives of various hybrid opto-electric techniques that have emerged over the last decade under a unified umbrella.

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Floating electrode optoelectronic tweezers: Light-driven dielectrophoretic droplet manipulation in electrically insulating oil medium

Cited by 56 publications

References 16 publications

Light-Driven Droplet Manipulation Technologies for Lab-on-a-Chip Applications

Light-Driven Droplet Manipulation Technologies for Lab-on-a-Chip Applications

Micro and Nano Manipulation and Assembly by Optically Induced Electrokinetics

Hybrid opto-electric manipulation in microfluidics—opportunities and challenges

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