This paper describes the experimental strategy developed to improve the modeling of liquidvapor flows during the chill down of rocket engines by cryogenic fluid in microgravity. A similarity analysis is performed to determine the relevant dimensionless numbers for the design of an experiment similar to engine flows. A literature review on reduced gravity quenching experiments, and on rewetting temperature and film boiling heat transfer shows the lack of validated models for microgravity. Experimental results obtained with the quenching of a glass tube by FC72 during parabolic flight are presented. Especially the impact of gravity and subcooling on rewetting temperature and film boiling heat transfer is investigated. Results show an increase in rewetting temperature, and a decrease in film boiling heat transfer under reduced gravity in agreement with the literature. The compar-B. Verthier (B) · C. Colin ison of 0 g flow pattern with corresponding tests on ground points out a behavior at 0 g closest to 1 g upflow than 1 g downflow.