The oblique flow compressor is one of the important components in the compressed air energy storage (CAES) system. The structural shape of the radial inlet chamber (RIC) directly affects the compressor performance, and a reasonable RIC design should achieve the smallest total pressure loss and outlet distortion as much as possible to meet the structural design. To study the influence of splitter blades, 4 RICs equipped with different numbers of splitter blades are designed, and the performance of 4 RICs and the overall performance of the compressor is calculated. The results show that with the increase in the number of splitter blades, the stall margin increases from 6.3% to 13.94%. At the design point, the isentropic efficiency is highest for the RIC with 17 splitter blades, and the pressure ratio is highest for the RIC with 11 splitter blades. Compared with the direct axial intake mode, the uniformity of the relative leakage distribution and the attack angle distribution of the impeller leading edge under 4 radial intake modes are poor. However, with an increase in the number of splitter blades, the uniformity of the relative tip leakage and the attack angle distribution gradually increase. The flow loss of RIC will increase simultaneously, though the uniformity of the outlet aerodynamic parameters distribution improves, and the influence on the downstream component performance gradually weakens. There is an optimal number of splitter blades in RIC, which balances the total pressure loss and distortion coefficient.