Flow controllable three-dimensional paper-based microfluidic analytical devices fabricated by 3D printing technology

Fu, Xianpeng; Xia, Bing; Ji, Baocheng; Shan, Lei; Zhou, Yan

doi:10.1016/j.aca.2019.02.046

Cited by 24 publications

(10 citation statements)

References 47 publications

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“…Increasing the binding of the color or enzyme in the case of enzymatic analysis of biomarkers could help overcome this issue. 45,50 Moreover, the color gradient is lower in some reservoirs. This is mainly because the amount of dye placed in the entrance section of the paper is higher compared to that in the other reservoirs.…”

Section: Sensors and Diagnostics Papermentioning

confidence: 99%

A wearable paper-integrated microfluidic device for sequential analysis of sweat based on capillary action

et al. 2022

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Section: Sensors and Diagnostics Papermentioning

confidence: 99%

A wearable paper-integrated microfluidic device for sequential analysis of sweat based on capillary action

et al. 2022

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“… Digital light processing 3D printed medical devices: (A) A limb with soft “muscle” and stiff “bone”[ 6 ], (B) spine-shaped phantom[ 32 ]. (C) Oral cavity model[ 33 ], (D) (i) nerve conduit with microchannels[ 7 ]; (ii) a range of nerve conduits[ 34 ], (E) zirconia dental implant[ 35 ], (F) detoxification device[ 8 ], (G) toxin sensor[ 36 ], (H) blood senor for measuring glucose, cholesterol, and triglycerides[ 37 ]. …”

Section: Medical Devicesmentioning

confidence: 99%

Digital Light Processing Based Three-dimensional Printing for Medical Applications

Zhang

Wang

et al. 2019

IJB

235

129

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An additive manufacturing technology based on projection light, digital light processing (DLP) 3D printing, has been widely applied in the field of medical products production and development. The precision projection light, reflected by a million pixels instead of a focused point, provides this technology both printing accuracy and printing speed. In particular, this printing technology provides a relatively milder condition to cells due to its non-direct contact. This review introduces the DLP-based 3D printing technology and its applications in medicine, including precise medical devices, functionalized artificial tissues and specific drug delivery systems. The products are particularly discussed for their significance for medicine. We believe that this technology provides a potential tool for biological research and clinical medicine, while challenges of scale-up and regulatory approval are also discussed.

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“…This method could transfer the fluid more easily and freely as required. Furthermore, the stacking method was applied in combination with a 3D-printing technique; the resin of the 3D printer was cured between the building platform and release paper along with the print design (Figure 3B) [88].…”

Section: Fabrication Techniquesmentioning

confidence: 99%

“…Three-dimensional paper-based microfluidic devices. ( A ) Stacking method using both-side adhesive tape (reprinted from ref [82] with permission from Elsevier, Copyright 2016), ( B ) 3D printer (reprinted from ref [88] with permission from Elsevier, Copyright 2019), ( C ) Origami method using wax-printed 2D paper sheets (reprinted from ref [95] with permission from Elsevier, Copyright 2017), ( D ) Double-sided 3D printing method using digital light processing printer (reproduced from ref [100] with permission from the Royal Society of Chemistry. 2018).…”

Section: Figurementioning

confidence: 99%

Fabrication, Flow Control, and Applications of Microfluidic Paper-Based Analytical Devices

2019

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Paper-based microfluidic devices have advanced significantly in recent years as they are affordable, automated with capillary action, portable, and biodegradable diagnostic platforms for a variety of health, environmental, and food quality applications. In terms of commercialization, however, paper-based microfluidics still have to overcome significant challenges to become an authentic point-of-care testing format with the advanced capabilities of analyte purification, multiplex analysis, quantification, and detection with high sensitivity and selectivity. Moreover, fluid flow manipulation for multistep integration, which involves valving and flow velocity control, is also a critical parameter to achieve high-performance devices. Considering these limitations, the aim of this review is to (i) comprehensively analyze the fabrication techniques of microfluidic paper-based analytical devices, (ii) provide a theoretical background and various methods for fluid flow manipulation, and iii) highlight the recent detection techniques developed for various applications, including their advantages and disadvantages.

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Flow controllable three-dimensional paper-based microfluidic analytical devices fabricated by 3D printing technology

Cited by 24 publications

References 47 publications

A wearable paper-integrated microfluidic device for sequential analysis of sweat based on capillary action

A wearable paper-integrated microfluidic device for sequential analysis of sweat based on capillary action

Digital Light Processing Based Three-dimensional Printing for Medical Applications

Fabrication, Flow Control, and Applications of Microfluidic Paper-Based Analytical Devices

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