Flow cytofluorometric evidence for the differential radioresponsiveness of aneuploid and diploid cervix tumours

DNA aneuploidy and low S-phase fraction as favourable prognostic signs in metastatic melanoma

“…Also regarding microcellular lung carcinoma near-diploid type tumours might be more resistant to chemotherapy than are hyperdiploid tumours (Abe et al, 1987). Interestingly, similar phenomenon to these have been observed in radiosen-sitivity of other malignancies: DNA aneuploid laryngeal carcinomas (Goldsmith et al, 1986), carcinomas of the oral cavities (Franzen et al, 1987) and the uterine cervix (Dyson et al, 1987), as well as bladder carcinomas (Jacobsen et al, 1987) have been reported as more radiosensitive than DNA diploid tumours. This probably has been contributed to a better prognosis for patients with DNA aneuploid tumours after curative radiotherapy in these tumour groups (Goldsmith et al, 1986;Franzen et al, 1987).…”

Alteration of Ki‐67, DNA content and cell cycle distribution during radiotherapy for cervix cancer

“…This accumulation of cells in G2 + M phase is a well-known process in radiobiology as one of the first identifiable changes in an irradiated population [20] and has also been reported in diploid tumors, but not in aneuploid ones [13].…”

Sinonasal Hemangiopericytomas: A Clinicopathologic and DNA Content Study

“…Eleven of the hemangiopericytomas were in the nasal cavity and three were exclusively in the paranasal sinuses (one maxillary, two ethmoid). The tumors had a mean major dimension of 3.0 cm (range, 14.0 to 2.3 cm) for the 10 for which this information was available.…”