Flow Injection-Capillary Electrophoresis (FI-CE): Recent Advances and Applications

Hanrahan, Grady; Dahdouh, Froseen; Clarke, Keith; Gomez, Frank A.

doi:10.2174/157341105774573938

Cited by 12 publications

(9 citation statements)

References 46 publications

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“…Actually, online CE‐MS of food contaminants is still quite challenging because, in CE, the interface is always a compromise between an optimal mass source performance and elevated separation efficiency. Indeed, the buffers or BGEs normally used for an optimal CE separation of food contaminants contain nonvolatile salts, like borate ions, or surfactants, like SDS, which noticeably improve the separation selectivity 50–52. These buffer additives impair a reliable mass detection.…”

Section: Ce Methodsmentioning

confidence: 99%

Sample preparation methods for the determination of pesticides in foods using CE‐UV/MS

2010

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Much progress has been made in pesticide analysis over the past decade, during this time hyphenated techniques involving highly efficient separation with sensitive detection have become the techniques of choice. Among these, methods based on separation with mass spectrometric detection have resulted in greater likelihood of identification and are acknowledged to be extremely useful and authoritative methods for the determination of pesticide residues but the inherent advantages of the use of CE as a separation technique are well-known and can be summarized as high separation efficiency, low analysis time, high resolution power, and low consumption of samples and reagents. Although UV is the most widely used detector in CE equipments so far so this detection mode is also included for the review. Even with such powerful instrumental techniques, however, the risk of interference increases with the complexity of the matrix studied, so sample preparation is often the limiting step in systems before instrumental analysis and is still mandatory in many applications, for example, food analysis. This article summarizes the analytical characteristics of the different methods of sample preparation for the determination of pesticide residues in a variety of food matrices, and surveys their recent applications in combination with CE using UV and MS detectors. We will discuss the advantages and the disadvantages of different methods, the instrumental aspects, summarize and conclude the perspectives for the future.

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Section: Ce Methodsmentioning

confidence: 99%

Sample preparation methods for the determination of pesticides in foods using CE‐UV/MS

2010

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“…Actually, online CE-MS of food contaminants is still quite challenging because, in CE, the interface is always a compromise between an optimal mass source performance and elevated separation efficiency. Indeed, the buffers or BGEs normally used for an optimal CE separation of food contaminants contain nonvolatile salts, like borate ions, or surfactants, like SDS, which noticeably improve the separation selectivity [14,15,25]. These buffer additives impair a reliable mass detection.…”

Section: Ce-msmentioning

confidence: 99%

“…The latest developments in capillary electromigration methods for the analysis of food and food components have been the subject of different reviews [13][14][15][16][17][18][19][20][21][22][23][24], as well as the principal applications of CE in the analysis of organic contaminants in food [25][26][27][28][29][30][31].…”

Section: Introductionmentioning

confidence: 99%

Application of capillary electrophoresis‐mass spectrometry for determining organic food contaminants and residues

et al. 2008

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Food contamination continues to be a serious problem around the world. Surveillance of chemical contaminants in foods is important not only for public health but also because of the negative economic impact of contamination. From the analytical perspective, analysis of contaminants in food is an extremely challenging area. There is a wide variety of questions, ranging from the quantification of extremely low levels of individual components to the detailed assessment and evaluation of the analytical technique possibilities. This review considers the applications of CE coupled to MS detection (CE-MS) for the analysis of organic contaminants in food. Analytical information on sample concentration techniques, as well as on the CE separation conditions and recoveries obtained from water and food are provided. Different sections include several fields of application, such as pesticides, drug residues, or toxic formed during food processing in different matrices. A number of tables report a comprehensive listing of CE-MS applications. As a result, this work presents an update overview on the principal application of CE-MS together with a discussion of their main advantages and drawbacks, and an outline of future trends on analysis of organic contaminants.

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“…Pervaporation has been coupled online to CE using a simple interface (a modified CE vial) that allowed volatile analytes (e.g., HSO À 3 ) to be isolated and interferences from complex matrices thus avoided [88]. Another option when the performance of a CE system can be improved at the stage of sample introduction concerns the application of flow injection (FI)-CE systems [89]. Recent advancements involved a miniaturized system with a CCD detector [90], applying negative pressure at the capillary outlet for a more reproducible sample introduction [91], and an arrangement, comprising two FI interfaces for the automated dual oppositeend sample injection (for the purpose of simultaneous determination of cations and anions) [92,93].…”

Section: Sample Preconcentrationmentioning

confidence: 99%

Recent trends in CE of inorganic ions: From individual to multiple elemental species analysis

Timerbaev

2007

Electrophoresis

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The major methodological developments in CE related to inorganic analysis are overviewed. This is an update to a previous review article by the author (Timerbaev, A. R., Electrophoresis 2004, 25, 4008-4031) and it covers the review work and innovative research papers published between January 2004 and the first part of 2006. As was underlined in that review, a growing interest of analytical community in providing elemental speciation information found a sound response of the CE method developers. Presently, almost every second research paper in the field of interest deals with element species analysis, the use of inductively coupled plasma MS detection and biochemical applications being the topics of utmost research efforts. On the other hand, advances in general methodology traditionally centered on a CE system modernization for improvements in sensitivity and separation selectivity have attracted less attention over the review period. While there is no indication that inorganic ion applications would surpass by the developmental rate the more matured analysis of organic analytes, CE can now be seen as an analytical technique to be before long customary in a number of inorganic analysis arenas.

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Flow Injection-Capillary Electrophoresis (FI-CE): Recent Advances and Applications

Cited by 12 publications

References 46 publications

Sample preparation methods for the determination of pesticides in foods using CE‐UV/MS

Sample preparation methods for the determination of pesticides in foods using CE‐UV/MS

Application of capillary electrophoresis‐mass spectrometry for determining organic food contaminants and residues

Recent trends in CE of inorganic ions: From individual to multiple elemental species analysis

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