Flow injection chemiluminescent determination of amiodarone in pharmaceutical preparations using photogenerated tris(2,2′-bipyridyl)ruthenium(III)

Pérez-Ruíz, Tomás; Martı́nez-Lozano, Carmen; Martı́n, Jesús; Ruiz, Encarna

doi:10.1016/j.jpba.2005.12.031

Cited by 7 publications

(2 citation statements)

References 23 publications

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“…This reagent was used as a powerful oxidant usually associated with photochemical generation of Ru(III) complexes. Many applications of the online photooxidation of ruthenium(II) complexes with peroxydisulphate have recently been reported (13,(33)(34)(35).…”

Section: +mentioning

confidence: 99%

Chemiluminescence determination of chlorpheniramine using tris(1,10‐phenanthroline)–ruthenium(II) peroxydisulphate system and sequential injection analysis

et al. 2008

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] and a peristaltic pump to propel the sample. The experimental conditions affecting the chemiluminescence reaction were systematically optimized, using the univariate approach. Under the optimum conditions linear calibration curves of 0.1-10 mg/ml were obtained. The detection limit was 0.04 mg/ml and the relative standard deviation (RSD) was always < 5%. The procedure was applied to the analysis of CPA in pharmaceutical products and was found to be free from interferences from concomitants usually present in these preparations.

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Section: +mentioning

confidence: 99%

Chemiluminescence determination of chlorpheniramine using tris(1,10‐phenanthroline)–ruthenium(II) peroxydisulphate system and sequential injection analysis

et al. 2008

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“…Various aminopolycarboxylic acids, amino alcohols and amines have been determined after separation by HPLC . Flow‐injection analysis has been carried out to determine amiodarone, l ‐cysteine and l ‐cystine using a Ru(bpy) 3 2+ –S 2 O 8 2− system in a UV photoreactor .…”

Section: Introductionmentioning

confidence: 99%

Photoinduced oxidation of a tris(2,2'‐bipyridyl)ruthenium(II)–peroxodisulfate chemiluminescence system for the analysis of mebeverine HCl pharmaceutical formulations and biological fluids using a two‐chip device

et al. 2013

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A new method for the analysis of mebeverine hydrochloride (MEB) has been developed using a two-chip device. The method is highly selective, sensitive, rapid and consumes minute amount of reagents. The developed method is free of interference from the degradation products of MEB and from common ingredients present in pharmaceutical formulations. The limit of detection was 0.043 µg/mL, and the limit of quantification was 0.138 µg/mL. The short analysis time per sample (20 s) allowed a large number of analyses to be performed within a very short time. Various samples were analyzed, including two different pharmaceutical formulations and a uniformity of content analysis for 20 tablets from a known batch and two biological samples at different concentrations. In addition, the method was compared with a validated high-performance liquid chromatography (HPLC) method and the results clearly indicated the suitability of the developed method for routine analyses. A new mechanism for the tris(2,2'-bipyridyl)ruthenium(II) (Ru(bpy)3 (2+) )-peroxodisulfate (S2 O8 (2-) ) chemiluminescence (CL) system has also been proposed. The mechanism is based on photoinduced oxidation of Ru(bpy)3 (2+) to Ru(bpy)3 (3+) via the formation of Ru(bpy)3 (2+) * upon irradiation with visible light. S2 O8 (2-) then oxidizes Ru(bpy)3 (2+) * to Ru(bpy)3 (3+) and the analyte subsequently reduces the resultant Ru(bpy)3 (3+) to Ru(bpy)3 (2+) *, which then produces the CL signal.

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Analytical applications of photoinduced chemiluminescence in flow systems—A review

Lara

Garcı́a-Campaña

Aaron³

2010

Analytica Chimica Acta

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Flow injection chemiluminescent determination of amiodarone in pharmaceutical preparations using photogenerated tris(2,2′-bipyridyl)ruthenium(III)

Cited by 7 publications

References 23 publications

Chemiluminescence determination of chlorpheniramine using tris(1,10‐phenanthroline)–ruthenium(II) peroxydisulphate system and sequential injection analysis

Chemiluminescence determination of chlorpheniramine using tris(1,10‐phenanthroline)–ruthenium(II) peroxydisulphate system and sequential injection analysis

Photoinduced oxidation of a tris(2,2'‐bipyridyl)ruthenium(II)–peroxodisulfate chemiluminescence system for the analysis of mebeverine HCl pharmaceutical formulations and biological fluids using a two‐chip device

Analytical applications of photoinduced chemiluminescence in flow systems—A review

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