Flow methods for the determination of polycyclic aromatic hydrocarbons using low power photomultiplier tube and charge coupled device chemiluminescence detection

Andrew, Kevin N.; Sanders, Matthew G.; Forbes, Stuart J.; Worsfold, Paul J.

doi:10.1016/s0003-2670(97)00052-4

Cited by 28 publications

(11 citation statements)

References 13 publications

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“…However, although the highest CL signal was obtained in 100% acetonitrile, the solutions of other three flow paths were prepared with doubly distilled water; the mixture of solutions from different flow paths affected the environment of TCPO solution. We also found that 100% acetonitrile solution dissolve the PTFE three-way mixer, which was a special requirement for the material of mixer; the same results were reported in previous work (Lin and Huie 1997;Andrew and Sandersa 1997). To avoid the problem, we added sodium dihydrogen phosphate and disodium hydrogen phosphate buffer (pH ¼ 7, with a final concentration of 0.1 M) to TCPO (TCPO had the highest reactivity between pH 5 and 9) and acetonitrile solution with 10% buffer=90% TCPO acetonitrile solution (v=v) (Lee, Je, Hur, et al 2003).…”

Section: Effect Of Solvents and Surfactantssupporting

confidence: 88%

Determination of Three Imidazole Derivatives by Flow-Injection Chemiluminescence

Sun

Tang

et al. 2009

Analytical Letters

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A rapid, simple, and sensitive method was developed for the determination of three imidazole derivatives based on their quenching effect on bis(2,4,6-tricholorophenyl) oxalate (TCPO)-H 2 O 2 chemiluminescence (CL) in the presence of rhodamine 6 G. Conditions affecting CL intensity were studied. With sodium dodecyl sulfate (SDS) as the additional agent, the relative standard deviation (RSD) was more twice the RSD without SDS. Under optimal conditions, good linear ranges were obtained from 1.0 Â 10 À4 g=mL to 1.0 Â 10 À6 g=mL, 1.0 Â 10 À5 g=mL to 1.0 Â 10 À7 g=mL, and 1.0 Â 10 À5 g=mL to 7.0 Â 10 À7 g=mL, with detection limits of 8.0 Â 10 À7 g=mL, 7.0 Â 10 À8 g=mL, and 8.0 Â 10 À8 g=mL (S=N ¼ 3) for hydrobenzole hydrochloride, thiamazole, and mizolastine, respectively. The RSDs for 13 consecutive injections of 1.0 Â 10 À6 g=mL hydrobenzole hydrochloride, thiamazole, and mizolastine were 1.89%, 1.47%, and 1.69%, respectively, and satisfied results were obtained with the method applied to their pharmaceutical preparations. The possible CL mechanism was simply discussed.

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Section: Effect Of Solvents and Surfactantssupporting

confidence: 88%

Determination of Three Imidazole Derivatives by Flow-Injection Chemiluminescence

Sun

Tang

et al. 2009

Analytical Letters

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“…Part-per-billion levels of gaseous hydrogen peroxide have been measured with a method based on 1,1'oxalyldi-imidazole-peroxyoxalate CL and incorporating a diffusion scrubber (100). The peroxyoxalate-hydrogen peroxide CL reaction has also been used in the determination of a range of polycyclic aromatic hydrocarbons (PAHs) at part-per-billion levels in synthetic hexane and acetonitrile solutions (121). This method of detection, in combination with chromatographic separation, could also prove suitable for the determination of PAHs in solvent-extracted atmospheric particulate samples.…”

Section: Atmospheric Samplesmentioning

confidence: 99%

Analytical applications of flow injection with chemiluminescence detection—a review

et al. 2001

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This paper reviews the literature on analytical applications of flow injection (FI) techniques with chemiluminescence (CL) detection from 1995-1999. The focus is on the application of FI-CL to the quantitative determination of specific analytes in real sample matrices. Therefore, entries have been tabulated under the most appropriate application area, ie pharmaceutical, environmental, foods and beverages and biomedical, as defined by the matrix that has been analysed. Each table lists analytes alphabetically and gives details of the exact sample matrix, the limit of detection (as reported in the original paper) and comments on the CL reaction used.

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“…The reagent itself is also nonfluorescent, thereby avoiding interferences in the FIA-CL detection, as a previous separation of the excess of reagent is not necessary. A disadvantage of CL detection involving the PO systems is the poor solubility and stability of oxalate esters in aqueous systems, which complicates their use in FIA systems, requiring the use of stainless steel devices [18] or special and expensive tubes [19], as normal tubes employed with peristaltic pumps are not resistant against acetonitrile, which is the most common solvent used for dissolving oxalate esters.…”

Section: Resultsmentioning

confidence: 99%

Determination of albumin in biological fluids by flow injection analysis using the peroxyoxalate chemiluminescent system in micellar medium

Gámiz‐Gracia

Garcı́a-Campaña

Barrero

et al. 2003

Analytical and Bioanalytical Chemistry

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A new sensitive analytical procedure for the determination of albumin is presented, based on the participation of a fluorescent derivative of the protein in the peroxyoxalate chemiluminescent system using imidazole as a catalyst. The chemiluminescent emission is detected in a flow injection analysis (FIA) system, employing micellar medium as carrier, whereas the derivatisation reaction is carried out off-line using fluorescamine as a label. The optimisation of the operational and chemical variables of the method such as concentration of reagents, flow-rates, injection volume, etc., involves the use of experimental designs, including Draper-Lin small composite design, scarcely used in analytical chemistry. The performance characteristics were established and a detection limit of about 0.1 fmol of albumin was obtained. The method has been validated and satisfactorily applied to the determination of albumin in human serum and urine.

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Flow methods for the determination of polycyclic aromatic hydrocarbons using low power photomultiplier tube and charge coupled device chemiluminescence detection

Cited by 28 publications

References 13 publications

Determination of Three Imidazole Derivatives by Flow-Injection Chemiluminescence

Determination of Three Imidazole Derivatives by Flow-Injection Chemiluminescence

Analytical applications of flow injection with chemiluminescence detection—a review

Determination of albumin in biological fluids by flow injection analysis using the peroxyoxalate chemiluminescent system in micellar medium

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