Flow pumping system for physiological waveforms

Tsai, William; Savaş, Ömer

doi:10.1007/s11517-009-0573-6

Cited by 31 publications

(27 citation statements)

References 10 publications

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“…This can for example be done by combining two separate power supplies, or two separate pumps (see e.g. Tsai and Savaş [12]).…”

Section: Conclusion and Recommendationsmentioning

confidence: 99%

“…To simulate physiologically realistic pulsatile flow, a dedicated pumping system is used in these experiments. This can either be a mock loop representing the full circulatory system [8,9], or a pump that reproduces a waveform measured locally in-vivo [4,5,6,7,12].…”

Section: Introductionmentioning

confidence: 99%

“…However, researchers often employ in-house built systems, for example because of cost considerations, or to add specific functionality. Examples of pumping systems that were developed to reproduce physiological waveforms are a gear pump driven by a stepper motor or servomotor, the rotation rate of which is controlled by a microcomputer (Hoskins et al [5]) or personal computer (Plewes et al [7]), a controlled piston pump (Chaudhury et al [4]), or a combination of both: a gear pump to deliver the steady flow component, and a piston pump to generate the pulsatile component (Tsai and Savaş [12]).…”

Section: Introductionmentioning

confidence: 99%

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Arduino control of a pulsatile flow rig

Drost

Kruif

Newport

2018

Medical Engineering & Physics

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This note describes the design and testing of a programmable pulsatile flow pump using an Arduino micro-controller. The goal of this work is to build a compact and affordable system that can relatively easily be programmed to generate physiological waveforms. The system described here was designed to be used in an in-vitro set-up for vascular access hemodynamics research, and hence incorporates a gear pump that delivers a mean flow of 900 ml/min in a test flow loop, and a peak flow of 1106 ml/min. After a number of simple identification experiments to assess the dynamic behaviour of the system, a feed-forward control routine was implemented. The resulting system was shown to be able to produce the targeted representative waveform with less than 3.6% error. Finally, we outline how to further increase the accuracy of the system, and how to adapt it to specific user needs.

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“…This can for example be done by combining two separate power supplies, or two separate pumps (see e.g. Tsai and Savaş [12]).…”

Section: Conclusion and Recommendationsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Arduino control of a pulsatile flow rig

Drost

Kruif

Newport

2018

Medical Engineering & Physics

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“…This has not been a limitation for the current application, since the range of Womersley numbers in much of the neurovasculature tends to be ≤ 1 (i.e., there is a minimal additive effect of multiple cardiac cycles) 35 , which suggests that steady-state conditions are sufficient to recapitulate discrete time points along the cardiac waveform in which the flow rate is comparable. However, for applications where the Womersley number is larger (e.g., vasculature closer to the heart), we envision a potential for introducing pulsatility through the use of an Arduino, which could be used to send the pump a time-varying PWM voltage waveform that enables the mimicking of a cardiac flow profile 36,37,38 .…”

mentioning

confidence: 99%

Meso-Scale Particle Image Velocimetry Studies of Neurovascular Flows <em>In Vitro</em>

Peck¹,

Bahena²,

Jahan³

et al. 2018

JoVE

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Particle image velocimetry (PIV) is used in a wide variety of fields, due to the opportunity it provides for precisely visualizing and quantifying flows across a large spatiotemporal range. However, its implementation typically requires the use of expensive and specialized instrumentation, which limits its broader utility. Moreover, within the field of bioengineering, in vitro flow visualization studies are also often further limited by the high cost of commercially sourced tissue phantoms that recapitulate desired anatomical structures, particularly for those that span the mesoscale regime (i.e., submillimeter to millimeter length scales). Herein, we present a simplified experimental protocol developed to address these limitations, the key elements of which include 1) a relatively low-cost method for fabricating mesoscale tissue phantoms using 3-D printing and silicone casting, and 2) an open-source image analysis and processing framework that reduces the demand upon the instrumentation for measuring mesoscale flows (i.e., velocities up to tens of millimeters/second). Collectively, this lowers the barrier to entry for nonexperts, by leveraging resources already at the disposal of many bioengineering researchers. We demonstratethe applicability of this protocol within the context of neurovascular flow characterization; however, it is expected to be relevant to a broader range of mesoscale applications in bioengineering and beyond.

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“…Instalación híbrida: Este tipo de instalaciones combinan una bomba (en principio no programable) que proporciona un flujo constante a un pistón, que es el encargado de crear el pulso en el caudal (Tsai & Savas, 2010). Esta opción tiene las ventajas e inconvenientes de caso anterior, añadiendo la ventaja de poder funcionar de forma indefinida de forma sencilla, y con el problema de tener que integrar un elemento más en la ya de por si compleja instalación.…”

Section: Instalaciones No Estacionariasunclassified

Estudio experimental del patrón de flujo en un modelo de una bifurcación coronaria con stent

Carrascal¹

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Valladolid, Septiembre de 2015 i Resumen La implantación de stents es una de las intervenciones más frecuentes que se aplican en arterias que han visto reducida su sección de paso por efecto de la ateroesclerosis. Permite a la zona afectada aumentar la sección de paso y reestablecer el flujo. No obstante, la presencia de stents puede modificar el patrón de flujo de tal manera que haga que la zona tienda reducir su sección de paso de nuevo (restenosis). El estudio de los efectos de los stents permitiría el desarrollo de geometrías y técnicas que minimicen tal efecto.El presente trabajo hace un estudio experimental del flujo en un modelo de bifurcación coronaria con stent. El objetivo es caracterizar el efecto de la presencia de distintos tipos de stent sobre el patrón de flujo en un modelo geométrico simplificado, bajo unas condiciones muy controladas.

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Flow pumping system for physiological waveforms

Cited by 31 publications

References 10 publications

Arduino control of a pulsatile flow rig

Arduino control of a pulsatile flow rig

Meso-Scale Particle Image Velocimetry Studies of Neurovascular Flows <em>In Vitro</em>

Estudio experimental del patrón de flujo en un modelo de una bifurcación coronaria con stent

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