Flowerlike CuO/Au Nanoparticle Heterostructures for Nonenzymatic Glucose Detection

Abstract

The controlled preparation of two-dimensional (2D) nanomaterials exhibiting heterojunction structures based on nontoxic and economical transition metal oxides represents breakthroughs in the electrochemistry field. Herein, flowerlike CuO/Au nanoparticles that have 2D nanomaterial characteristics and excellent glucose sensing performance were prepared by microwave hydrothermal synthesis of sea urchinlike CuO and subsequent self-generated acid etching of the sea urchinlike CuO in the presence of HAuCl 4 and NaBH 4 . HAuCl 4 was not only the reactant for the authigenic acid etching, but also the raw material for the heterojunction structure. Upon the acid etching, Au nanoparticles with an average size of 15 nm were uniformly distributed on the surface of CuO nanoflakes. Benefiting from a large specific surface area and low electron transfer resistance, the flowerlike CuO/Au nanoparticles were excellent electrode modification materials: glucose sensors based on the glassy carbon electrodes modified by the flowerlike CuO/Au nanoparticles demonstrated high sensitivity (2455 μA•mM −1 •cm −2 ), wide detection range (0.01−12 mM), low detection limit (0.53 μM), good stability, good reproducibility, and good selectivity. The green and economical authigenic acid etching method presented in this study exemplifies the controlled preparation of 2D nanomaterials with specific properties.

Electrochemical Sensor for the Anti‐tuberculosis Drug Rifampicin on CuO@rGO‐Nanocomposite‐Modified GCE by Voltammetry Techniques

“…[23] Recently, Wang et al investigated non-enzymatic glucose detection with CuO/Au nano-particle. [24] Chen et al sensed room temperature NO 2 via CuO nanorods functionalised with Au nanoparticles. [25] The integration of noble metal nano particles significantly improved the electrochemical properties as well as effective cost.…”

“…Recently, Wang et al. investigated non‐enzymatic glucose detection with CuO/Au nano‐particle [24] . Chen et al.…”

An amphiprotic paper-based electrode for glucose detection based on layered carbon nanotubes with silver and polystyrene particles

“…In the process, the fabricated organic composite electrodes were prone to breaking due to their fragileness. 39 Also, the sensitivity and detection limit of available paper electrodes to glucose 1,[40][41][42][43][44][45][46][47][48] still need to be further improved.…”

“…This phenomenon indicated that the hydrophilic side of the paper electrode was critical to the glucose detection, in agreement with the previous reports. [40][41][42][43][46][47][48]76,77 Possible reasons could be ascribed to the fact that glucose is a polar molecule and has more tendency to adsorb on the hydrophilic back side of the electrode relative to the hydrophobic front side. When the hydrophilic side was shielded with hydrophobic adhesive tape, the possibility of adsorbing glucose on the electrode became low, thus leading to a poor electrochemical performance.…”

“…Upon the successive addition of glucose, the fabricated electrode exhibited a rapid and sensitive response, and 98% steady state 1), the detection limit and sensitivity of CNT-NH 2 -Ag/PS-based electrode were indeed superior to most of them. 1,[40][41][42][43][44][45][46][47][48]76,79,80 The higher sensitivity of the fabricated electrode could be attributed to the unique hydrophobic/hydrophilic properties and interactions between Ag and amino groups bonded on the surface of CNTs. This enabled a fast adsorption of glucose on the surface of the paper substrate and direct conduction of electrons between glucose and the CNT-NH 2 -Ag/PS electrode.…”