Fluence rate distribution in laser-induced interstitial thermotherapy by mesh free collocation

Xu, Xiao; Meade, Andrew; Bayazıtoğlu, Yıldız

doi:10.1016/j.ijheatmasstransfer.2010.05.020

Cited by 13 publications

(5 citation statements)

References 23 publications

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“…Modifications to speed the calculation and increase accuracy of the RTE equation have also been proposed. 90 Note that all of these approximations should be used with care and special attention should be paid to the applicable conditions and desirable accuracy, for example the failure of DA for higher gold nanoshell concentration discussed here. 86 Another approach to evaluate light transport or fluence in GNP laden tissues involves Monte Carlo ray tracing to directly simulate photon transport in tissues.…”

Section: Laser Fluence Estimation In Tissue With Gnpsmentioning

confidence: 99%

Thermophysical and biological responses of gold nanoparticle laser heating

2012

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A compelling vision in nanomedicine is the use of self directed nanoparticles that can accumulate in areas of disease to perform designed functions, such as molecular delivery or destruction, endosomal release of genes or siRNA, and selective cell or tumor destruction with nano to macroscale spatiotemporal control and precision. These functions are increasingly achieved by gold nanoparticles (GNPs, such as sphere, shell or rod) that can be activated with a laser "switch". A defining aspect of this "switch" is GNP absorption of laser light and the ensuing heat generation and temperature change that can be confined or propagated through multiple scales from the nanoparticle surface up through bulk biological cells and tissues. In this critical review, we discuss the fundamental mechanisms of laser GNP heat generation, the measurement and modelling of the ensuing thermal response, and a number of the evolving biological applications dependent on this new technology (181 references).

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Section: Laser Fluence Estimation In Tissue With Gnpsmentioning

confidence: 99%

Thermophysical and biological responses of gold nanoparticle laser heating

2012

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“…For the problem under consideration, one can refer to papers [21,22], in which the MC method is used in biomedical applications. Further information can be found in paper [23], in which a mesh free collocation method for complete RTE is presented.…”

Section: Radiative Transfer Modeling Based On P1 Approximationmentioning

confidence: 99%

Simplified Approaches to Radiative Transfer Simulations in Laser-Induced Hyperthermia of Superficial Tumors

Dombrovsky

Randrianalisoa

Lipínski

et al. 2013

Comput Thermal Scien

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“…Numerical solutions to the unsimplified integral–differential radiant transport equation (RTE) [27] utilise the least assumptions and provide the most flexibility in terms of applications. The standard diffusion approximation characterises the diffuse radiance at position x propagating in direction ω ( Note that this is not the same as the perfusion ω( u, x )) as the first two terms of a Legendre polynomial series expansion.…”

Section: Mathematical Modelling Aspectsmentioning

confidence: 99%

Model-based planning and real-time predictive control for laser-induced thermal therapy

Feng

Fuentes

2011

International Journal of Hyperthermia

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In this article, the major idea and mathematical aspects of model-based planning and real-time predictive control for laser-induced thermal therapy (LITT) are presented. In particular, a computational framework and its major components developed by authors in recent years are reviewed. The framework provides the backbone for not only treatment planning but also real-time surgical monitoring and control with a focus on MR thermometry enabled predictive control and applications to image-guided LITT, or MRgLITT. Although this computational framework is designed for LITT in treating prostate cancer, it is further applicable to other thermal therapies in focal lesions induced by radio-frequency (RF), microwave and high-intensity-focused ultrasound (HIFU). Moreover, the model-based dynamic closed-loop predictive control algorithms in the framework, facilitated by the coupling of mathematical modelling and computer simulation with real-time imaging feedback, has great potential to enable a novel methodology in thermal medicine. Such technology could dramatically increase treatment efficacy and reduce morbidity.

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Fluence rate distribution in laser-induced interstitial thermotherapy by mesh free collocation

Cited by 13 publications

References 23 publications

Thermophysical and biological responses of gold nanoparticle laser heating

Thermophysical and biological responses of gold nanoparticle laser heating

Simplified Approaches to Radiative Transfer Simulations in Laser-Induced Hyperthermia of Superficial Tumors

Model-based planning and real-time predictive control for laser-induced thermal therapy

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