Fluidodinâmica Computacional (CFD) para Prever Alterações Patológicas na Aorta: Está Pronta para Uso Clínico?

Obrist, Dominik; Tengg-Kobligk, Hendrik von

doi:10.36660/abc.20220040

Cited by 4 publications

(2 citation statements)

References 15 publications

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“…Therefore, in the present work, we studied the hemodynamic changes of the LSA using an endograft covering half the ostium of the LSA. In order to provide valuable reference for clinical treatment, CFD was applied to analyze the changes in common indices, such as the blood ow eld, the blood velocity distribution, and the blood pressure on the arterial wall in the LSA after implantation of endograft [14].…”

Section: Introductionmentioning

confidence: 99%

Hemodynamic changes for half cover Left subclavian artery ostium during thoracic endovascular aortic repair

Li,

Wen,

Yuan

et al. 2024

Preprint

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Some clinicians use endograft to cover half the left subclavian artery (LSA) ostium to cure some cases with insufficient landing area in thoracic endovascular aortic repair(TEVAR) treatment. So we used computational fluid dynamics (CFD) to study the hemodynamic changes on LSA, because they may cause acute thrombosis or arteriosclerosis of LSA. Methods The digital model of the aortic arch was established and named model A, which only included supraarch branch the LSA. By directly covering half of the LSA ostiumto simulate half cover LSA ostium as model B. All established models were imported into the Gambit grid division software for grid division and were subsequently imported into the Fluent software for hemodynamic numerical simulation and calculation. The related changes for hemodynamic parameters of LSA were analyzed and compared. Results Under the same aortic inlet flow, in model B, the local blood flow velocity of LSA ostium increased and whole blood flow velocity at the distal end decreased. The average wall shear stress(WSS) of the LSA was significantly decreased. Meanwhile there was an obvious turbulent flow in the LSA lumen, and the related blood flow state was disordered. Conclusion CFD research confirmed that the implantation of an endograft covering half the LSA ostium can cause obvious hemodynamic changes, which is likely to cause a long-term hardening or an acute thrombosis of the LSA, finally increased the risk of stroke. Once this operation is performed in some specific clinical cases for simplicityand economy, we should actively anticoagulate and follow up regularly.

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Section: Introductionmentioning

confidence: 99%

Hemodynamic changes for half cover Left subclavian artery ostium during thoracic endovascular aortic repair

Li,

Wen,

Yuan

et al. 2024

Preprint

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show abstract

“…Therefore, in the present work, we studied the hemodynamic changes of the LSA using two surgical methods: an endograft partially covering the ostium of the LSA and a MFM implantation. In order to provide valuable reference for clinical treatment, CFD was applied to analyze the changes in common indices, such as the blood ow eld, the blood velocity distribution, and the blood pressure on the arterial wall in the LSA after implantation of two kinds stents [24].…”

Section: Introductionmentioning

confidence: 99%

Effects of two different surgical methods for endovascular repair of the thoracic aorta on the hemodynamics of the left subclavian artery

Li,

Yuan,

Wen

et al. 2023

Preprint

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Background: Some clinicians use endograft to partially cover the left subclavian artery (LSA) ostium or multilayer flow modulator (MFM) to mitigate cases with an insufficient landing area in thoracic endovascular aortic repair(TEVAR) treatment. So we used computational fluid dynamics (CFD) to study the effects of two surgical methods on the hemodynamics of the LSA, due to they may affect the long-term patency rate of the LSA. Methods: The digital model of the aortic arch was established and named model A, which only included supraarch branch the LSA. The simulated digital model of the MFM was implanted into model A, named as model B. By directly covering one half of the LSA ostium, which was named as model C. All established models were imported into the Gambit grid division software for grid division and were subsequently imported into the Fluent software for hemodynamic numerical simulation and calculation. The changes in the related hemodynamic parameters of the LSA after implantation of the two stents were analyzed and compared. Results: Under the same aortic inlet flow, in model C, the lumen flow of the LSA was obviously reduced and the distal descending aorta flow was increased, the local blood flow velocity of LSA ostium increased and whole blood flow velocity at the distal end decreased. The average wall shear stress(WSS) of the LSA was significantly decreased. Meanwhile there was an obvious turbulent flow in the LSA lumen, and the related blood flow state was disordered. However, all changes in model B was occured, they changed slightly compared with model A. Conclusion: CFD research confirmed that the implantation of an MFM had little influence on the hemodynamics of the LSA. In contrast, the implantation of an endograft partially covering the LSA ostium increased the local ostium velocity. But it reduced the global flow rate, velocity, and average wall shear stress at the distal end. This change is likely to cause a long-term hardening and an acute thrombosis of the LSA artery. Nevertheless, this operation can also be used in specific clinical cases.

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Utility of computational fluid dynamics for prediction of efficacy of the surgical interventions for aortic coarctation in adults

Fujisue¹,

Takayama²,

Tonoki³

et al. 2023

JTCVS Techniques

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Fluidodinâmica Computacional (CFD) para Prever Alterações Patológicas na Aorta: Está Pronta para Uso Clínico?

Cited by 4 publications

References 15 publications

Hemodynamic changes for half cover Left subclavian artery ostium during thoracic endovascular aortic repair

Hemodynamic changes for half cover Left subclavian artery ostium during thoracic endovascular aortic repair

Effects of two different surgical methods for endovascular repair of the thoracic aorta on the hemodynamics of the left subclavian artery

Utility of computational fluid dynamics for prediction of efficacy of the surgical interventions for aortic coarctation in adults

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