2020
DOI: 10.1016/j.ejmp.2020.09.018
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FLUKA simulation of target fragmentation in proton therapy

Abstract: In proton therapy, secondary fragments are created in nuclear interactions of the beam with the target nuclei. The secondary fragments have low kinetic energies and high atomic numbers as compared to primary protons. Fragments have a high LET and deposit all their energy close to the generation point. For their characteristics, secondary fragments can alter the dose distribution and lead to an increase of RBE for the same delivered physical dose. Moreover, the radiobiological impact of target fragmentation is … Show more

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Cited by 9 publications
(4 citation statements)
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“…FLUKA can simulate the whole track of several particles like photons, electrons, neutrons, and hadrons on a wide range of energies. It has been widely used for high-energy physics, experiencing an increasing application for medical physics purposes [ 62 , 63 ]. FLUKA implements an original algorithm for treating multiple scattering on charge particles transport based on the Bethe improved Moliere’s theory [ 64 ].…”
Section: Methodsmentioning
confidence: 99%
“…FLUKA can simulate the whole track of several particles like photons, electrons, neutrons, and hadrons on a wide range of energies. It has been widely used for high-energy physics, experiencing an increasing application for medical physics purposes [ 62 , 63 ]. FLUKA implements an original algorithm for treating multiple scattering on charge particles transport based on the Bethe improved Moliere’s theory [ 64 ].…”
Section: Methodsmentioning
confidence: 99%
“…This was attributed to PHITS underestimating the probability of fragment production [70]. Using the Monte Carlo particle transport code FLUKA [72], the energy distribution, range distribution, and fragment fluence were studied for H, He, Li, B, Be, C, N, and O in proton-induced reaction on water between 40 and 200 MeV [73]. The energy distribution was highly asymmetric.…”
Section: Simulation Studiesmentioning
confidence: 99%
“…Several computational codes, based on Monte Carlo simulation, have been used in radiological protection, radiotherapy source dosimetry, planning systems, and other applications PENELOPE [1][2][3][4][5][6], MCNP [7][8][9][10][11], EGSnrc [12][13][14][15], FLUKA [16][17][18][19][20], TOPAS [21][22][23][24][25], GAMOS [26][27][28][29], Geant [30,31].…”
Section: Introductionmentioning
confidence: 99%