Fluorescein‐Labeled Starch Maleate Nanoparticles as Sensitive Fluorescent Sensing Probes for Metal Ions

Chin, Suk Fun; Aressa, Azman; Pang, Suh Cem; Ng, Sing Muk

doi:10.1155/2014/108359

Cited by 10 publications

(5 citation statements)

References 31 publications

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“…Chin, Azman, Pang, and Ng (2014) and Li et al. (2011) synthesized nanoparticles with fluorescein isothiocyanate covalently attached to the starch acetate (FISM).…”

Section: Applications Of Starch‐based Nanoparticlesmentioning

confidence: 99%

Starch‐based nanoparticles: Stimuli responsiveness, toxicity, and interactions with food components

Wang

et al. 2020

Comp Rev Food Sci Food Safe

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In recent years, starch‐based nanoparticles have attracted great interest due to their small size, good biocompatibility, and environmental friendliness, as well as their potential applications in foods, drug delivery carriers, and biodegradable edible films. Compared with nonstarch polysaccharides, starch can be enzymatically hydrolyzed into glucose in vivo, so it can be used as an enzyme‐responsive carrier. The recent research progress of starch‐based nanoparticles, including starch nanoparticles, starch nanospheres, starch micelles, starch vesicles, starch nanogels, and starch nanofibers, are reviewed in this paper. The main focus is on their responsiveness, digestibility, toxicity, interactions with other components, and applications. Starch‐based nanoparticles are nontoxic and responsive to pH, temperature, light, and other stimuli. It can interact with proteins, antioxidants, and lipids through electrostatic interactions and hydrogen bonding interactions. Starch‐based nanoparticles have a wide range of applications, including enhancing the mechanical properties of films and gels, stabilizing emulsions, as a fluorescent indicator, a catalyst, and a nanocarrier to control the release of active ingredients and drugs.

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“…Chin, Azman, Pang, and Ng (2014) and Li et al. (2011) synthesized nanoparticles with fluorescein isothiocyanate covalently attached to the starch acetate (FISM).…”

Section: Applications Of Starch‐based Nanoparticlesmentioning

confidence: 99%

Starch‐based nanoparticles: Stimuli responsiveness, toxicity, and interactions with food components

Wang

et al. 2020

Comp Rev Food Sci Food Safe

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“…Qaqish et al The final compound was analyzed by FTIR and 1 H NMR (Figure S4). Because the starting molar ratio of starch to FITC was very low (50:1), it was difficult to finely see the presence of FITC, but by IR, excepting the characteristic peaks from starch molecule, additional absorption peaks between 1590 and 1450 cm –1 could be observed, which could refer to the CC stretching from the benzene ring . In addition, a low-intensity signal was detected between 6 and 7 ppm in the 1 H NMR spectra and could fit with the ring protons of the FITC.…”

Section: Results and Discussionmentioning

confidence: 89%

Design of Polyamine-Grafted Starches for Nucleotide Analogue Delivery: In Vitro Evaluation of the Anticancer Activity

et al. 2016

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Nucleotide analogues are a therapeutic class that is very promising and currently used in clinics, notably against viral infectious diseases and cancer. However, their therapeutic potential is often restricted by a poor stability in vivo, the induction of severe side effects, and limited passive intracellular diffusion due to their hydrophilicity. Polysaccharide-based polymers (e.g., starch) have considerable advantages, including a lack of toxicity and the absence of antigenicity. The aim of this study was to develop new cationic starches able to form complexes with nucleotide analogues, thus protecting them and increasing their cell uptake. At the same time, the material should demonstrate good biocompatibility and low cytotoxicity. Different polyamines, (TREN, TEPA, and spermine) were grafted to starch to evaluate the impact of side-chain properties. The resulting cationic starch derivatives were characterized (e.g., degree of modification) and compared in their ability to form polyplexes with ATP as a model nucleotide. Among the tested candidates, the formulation of starch-TEPA and ATP with an N/P ratio of 2 led to nanoparticles with a size of 429 nm, a PdI of 0.054, and a ζ potential of -9 mV. MTT and LDH assays on A549 cell line showed low toxicity for this polymer. Confocal microscopy study proved that the cell internalization was an incubation-time- and energy-dependent process. Most important, starch-TEPA complexed with ddGTP showed significant biological activity on A549 cancer cells compared to that of plain ddGTP at the same concentration.

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“…Silver (Ag+) and lead (Pb 2+ ) ions can suppress the fluorescent of FISM nanomaterials in a concentration-dependent approach. These are the first to show that FISM nanoparticles may be used as affordable and convenient fluorescence sensor sensors for Ag+ and Pb 2+ ions, having limits of detection of 2:55 × 10 −5 M and 3:64 × 10 −5 M, correspondingly [13].…”

Section: Related Workmentioning

confidence: 93%

Detection of Ag+ by Synthesizing Fluorescent Copper Nanoparticles through Ultrasensitive Free Label Approach

Arthy

Brindha²,

Viswanathan

et al. 2022

Journal of Nanomaterials

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Ag is abundant in nature and is employed in practically every aspect of life. Furthermore, Ag+ contamination poses a severe hazard to human and environmental health due to the extensive usage of Ag products. Traditional Ag+ detection techniques include drawbacks such as high operational costs, sophisticated operating units and instruments, and strong technical demands. The use of fluorescence copper nanoparticles in pollution detection has received a lot of attention in recent times. The development of copper nanoparticles and the detecting of Ag+ are the major topics of this research. Utilizing fluorescence copper nanoparticles produced utilizing glucose (Glc) as a reduction mediator like a fluorescent probe, and a simple approach for determining Ag+ in water was devised. Due to its appealing properties, including such dissolution rate, widespread availability, simplicity of synthesis process, and excellent biocompatibility, fluorescence copper nanoparticles (F-CuNPs) have sparked a lot of interest, and a lot of time and effort has gone into their synthesis and usage. The slightly elevated metallophilic Ag+ contact served as such sensing element, efficiently quenching the fluorescent of AuAg NCs. Moreover, these fluorescence nanoprobes could have been used to identify Ag+ in the atmosphere, implying that they might be used as practical, dual-functional, fast-responding, and label-free fluorescent sensors for health and environmental assessment. The experiment’s analytical methodology would be that silver ions could fast and efficiently extinguish the fluorescent of Glucose-CuNPs. In the Ag+ region at 100 mol/L–600 mol/L ( R = 0 9845 ), a strong linear relation was discovered; the color is progressively improved below the observable region and visually colorimetrical measurement. Furthermore, the Glucose-CuNP instrument only detected Ag+ and was unaffected by other metal ions, demonstrating that Glucose-CuNPs have strong sensitivity for Ag+ sensing. Glucose-CuNP, as a result, accomplishes the identification of substantial metal Ag+ ions, and it has promising future applicability in environmental monitoring.

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Fluorescein‐Labeled Starch Maleate Nanoparticles as Sensitive Fluorescent Sensing Probes for Metal Ions

Cited by 10 publications

References 31 publications

Starch‐based nanoparticles: Stimuli responsiveness, toxicity, and interactions with food components

Starch‐based nanoparticles: Stimuli responsiveness, toxicity, and interactions with food components

Design of Polyamine-Grafted Starches for Nucleotide Analogue Delivery: In Vitro Evaluation of the Anticancer Activity

Detection of Ag+ by Synthesizing Fluorescent Copper Nanoparticles through Ultrasensitive Free Label Approach

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