Fluorescence-based assay probing regulator of G protein signaling partner proteins

Rapid identification of pathogens responsible for necrotizing fasciitis on an integrated microfluidic system

“…The high morbidity and mortality rate associated with fascial infections known as necrotizing fasciitis (NF) has not diminished appreciably since the disease was first described over 60 years ago. 1,2 The length of time required for accurate pathogen detection is partially responsible for such a poor prognosis, especially given the aggressive nature of most NF infections. 3 Patient prognosis and survival can be improved by providing nutritional support and by directly treating the infected tissues (e.g., debridement) through surgical intervention, even by limb amputation, which is sometimes life-saving.…”