Fluorescence of nucleic acid — Terbium(III) complexes

Formoso, Carl

doi:10.1016/0006-291x(73)90575-5

Cited by 64 publications

(20 citation statements)

References 7 publications

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“…Ln 3+ interact with several kinds of constituents of living organisms and these interactions have been used to investigate properties of phospholipids (Hutton, Yeagle & Martin, 1977), nucleic acids (Formoso, 1973;Kayne & Cohn, 1974;Jones & Kearns, 1974;Wolfson & Kearns, 1975;Ringer, Burchett & Kizer, 1978), and proteins. In many of the above examples from cellular systems it is likely that non-specifically bound Ln 3+ interact primarily with phospholipids and some proteins while specifically bound Ln 3+ have displaced Ca 2+ (or Mg 2+ ) from proteins.…”

Section: Ln 3 + In Biological Systemsmentioning

confidence: 99%

Lanthanides as probes for calcium in biological systems

Martin

Richardson

1979

Quart. Rev. Biophys.

362

181

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Calcium ion plays an essential role in many biological processes. The environment about Ca2+ may be probed by substitution of tripositive lanthanide ions, Ln3+. Ca2+ proteins fall into two broad classes: those that are inhibited by Ln3+ substitution and those that are not. It is suggested that although Ca2+ undertakes a primarily structural role in the Ln3+ non-inhibited proteins, Ca2+ may be near the active site or participate in the mechanism of action of Ln3+ inhibited proteins. Ca2+ and Ln3+ radii are similar; most Ln3+ are slightly larger than Ca2+ in complexes of the same coordination number, and substitution of Ln3+ for Ca2+ is accommodated by a slight decrease in bond distance or by an increase in coordination number. Luminescence from Tb3+ has been demonstrated to be a sensitive environmental probe of Ca2+ binding sites in proteins.

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Section: Ln 3 + In Biological Systemsmentioning

confidence: 99%

Lanthanides as probes for calcium in biological systems

Martin

Richardson

1979

Quart. Rev. Biophys.

362

181

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“…Tb 3+ ion with a high-energy excited state ( 5 D 4 , 20500 cm −1 ) as an energy acceptor matches the ET which lies in blue or shorter wavelength regions, resulting in the typical emission of Tb 3+ ion arising from its 5 D 4 excited state to 7 F 6 , 7 F 5 , 7 F 4 and 7 F 3 ground state with the peaks at 490, 544, 585 and 624 nm, respectively and the most intensity centralizes at 544 nm (picture c in Scheme 1D) (Fu et al, 1999). Since nucleic acids exhibit large absorption cross sections, and the triplet state of nucleic acids is slightly higher in energy than the 5 D state of the Tb 3+ , the ET from the excited base to the emissive 5 D 4 state of bound Tb 3+ is possible (Formoso et al, 1973;Nagesh et al, 1992). The luminescence character of Tb 3+ in our system was studied with luminescence and UV-vis absorption spectroscopy.…”

Section: Energy Transfer (Et) and Various Electronic Transitions In Dmentioning

confidence: 98%

[G3T]5/Tb3+ based DNA biosensor with target DNA-triggered autocatalytic multi-cycle-amplification and magnetic nanoparticles assisted-background-lowered

Jiang

Zhang

Wang

2015

Biosensors and Bioelectronics

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“…their stability under physiological conditions is rather unlikely. By way of contrast, highly charged metal ions such as the lanthanides [24,25] ajg bound tightly enough to withstand isolation from biological tissues. Iron (III) complexes between ATP and GTP were successfully isolated from both human and rat red cells' 26 !.…”

Section: X-ray Photoelectron Spectrometry Of Copper-thiouracil Complexesmentioning

confidence: 98%

X-Ray Photoelectron Spectrometry of Copper-Thiouracil Complexes

Thomas¹,

Weser²

1977

Hoppe-Seyler´s Zeitschrift für physiologische Chemie

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X-ray photoelectron spectrometry was applied to evaluate the correct oxidation number of copper in complexes with 2-thiouracil, 6-amino-2-thiouracil and 6-methyl-2-thiouracil. Regardless of the mode of preparation exclusively Cu(I) was bound to the different thiouracil compounds, producing one homogeneous signal of the Cu2p3/2 electrons at 932.5 eV. Upon oxidation with H2O2, a typical Cu(II) satellite appeared in the main signal of the Cu2p3/2 level was shifted to higher binding energy values. The reaction of Cu(II) with thioracil yielded identical complexes as above, in which Cu had the formal oxidation state +I. During this reaction portions of the thiouracil were oxidized to 2,2'-dithiobis(4-pyrimidinol) [bis(4-hydroxy-2-pyrimidinyl)disulphide], as seen by the shifted sulphur 2p signals to 163.5 eV. After treating the Cu-thiouracil complexes with H2O2, the simultaneous presence of sulphur species having the oxidation states RStheta (161 eV), RSSR (163.5 eV) and RSOtheta3 (168.5 eV) is indicated by the ESCA signals monitored.

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Fluorescence of nucleic acid — Terbium(III) complexes

Cited by 64 publications

References 7 publications

Lanthanides as probes for calcium in biological systems

Lanthanides as probes for calcium in biological systems

[G3T]5/Tb3+ based DNA biosensor with target DNA-triggered autocatalytic multi-cycle-amplification and magnetic nanoparticles assisted-background-lowered

X-Ray Photoelectron Spectrometry of Copper-Thiouracil Complexes

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