“…[7][8][9][10][11][12][13][14][15] Fluorescein and rhodamine B exhibit excellent photophysical properties, such as quantum yield and photophysical stability and are widely utilized fluorophores in applications of cellular imaging and biotechnology. [16][17][18][19][20][21][22] Because of their high fluorescence and deep color, both these fluorophores have been widely used as fluorogenic platforms for sensing of pH, metal ions, and a variety of chemicals. Their efficient and noticeable fluorescence changes stem from the reversible ringopening and ring-closure of the lactone and lactam rings in fluorescein and rhodamine, respectively, upon exposure to external stimuli, leading to emission color changes.…”