Synthesis of a glucose oxidase-conjugated, polyacrylamide-based, fluorescent hydrogel for a reusable, ratiometric glucose sensor

Kim, Yong-Kyun; Namgung, Ho; Lee, Taek Seung

doi:10.1039/c6py01120a

Cited by 22 publications

(29 citation statements)

References 54 publications

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“…Obviously, there are other mechanisms available: Kim et al [80] in fact developed an optical biosensing platform encapsulating in peptide hydrogel networks enzyme bio receptors (GOX) in combination with fluorescent reporters (functionalized quantum dots QDs): photoluminescence quenching of the hybridized QDs permitted the detection of glucose. Recently new fluorescent optical methods for glucose detection were developed: an example is provided by the work of 2016 of Kim and co-workers [81]. They proposed a new hydrogel sensor based on a copolymer realized of acrylamide and fluorescent monomers of fluorescein and rhodamine B. GOX was immobilized in the hydrogel matrix which was pH responsive and could change fluorescence colors with pH changes.…”

Section: Physicochemical Sensormentioning

confidence: 99%

Progress in hydrogels for sensing applications: a review

Pinelli

Magagnin

Rossi

2020

Materials Today Chemistry

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There are several developments taking place in the field of sensors driven by the world today requirements. One of the most important novelties of the last two decades in the field is represented by the hydrogel-based sensors which constitute a wide family of innovative smart sensing devices relevant for many different applications. Hydrogels in fact are hydrophilic, biocompatible and highly water swellable polymer networks able to convert chemical energy into mechanical energy, with the great peculiarity to be able to respond to external stimuli. These characteristics have ensured them considerable recognition as valuable tool for smart sensing and diagnostics. The aim of this review is to focus on the advances obtained in the field in the last ten years.

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Section: Physicochemical Sensormentioning

confidence: 99%

Progress in hydrogels for sensing applications: a review

Pinelli

Magagnin

Rossi

2020

Materials Today Chemistry

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“…Furthermore, the somewhat challenging synthesis and lack of proteolytic stability of tripeptides could limit the versatility of this approach in certain applications. GOx has also been extensively incorporated into hydrogel materials for a wide range of other applications, including glucose sensors [41][42][43][44] , glucose-swellable materials 45,46 , redox hydrogel-modified electrodes 47,48 , and drug delivery depots 49,50 .…”

Section: Honey-inspired Antimicrobial Hydrogels Resist Bacterial Colomentioning

confidence: 99%

Honey-inspired antimicrobial hydrogels resist bacterial colonization through twin synergistic mechanisms

Zhang

Gunatillake

et al. 2020

Sci Rep

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Inspired by the interesting natural antimicrobial properties of honey, biohybrid composite materials containing a low-fouling polymer hydrogel network and an encapsulated antimicrobial peroxide-producing enzyme have been developed. These synergistically combine both passive and active mechanisms for reducing microbial bacterial colonization. The mechanical properties of these materials were assessed using compressive mechanical analysis, which revealed these hydrogels possessed tunable mechanical properties with Young’s moduli ranging from 5 to 500 kPa. The long-term enzymatic activities of these materials were also assessed over a 1-month period using colorimetric assays. Finally, the passive low-fouling properties and active antimicrobial activity against a leading opportunistic pathogen, Staphylococcus epidermidis, were confirmed using bacterial cell counting and bacterial adhesion assays. This study resulted in non-adhesive substrate-permeable antimicrobial materials, which could reduce the viability of planktonic bacteria by greater than 7 logs. It is envisaged these new biohybrid materials will be important for reducing bacterial adherence in a range of industrial applications.

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“…), fluorescent hydrogel materials can exert beneficial effects on optoelectronic devices, sensors, displays, etc. . For instance, Lee and colleagues have established a fluorescent hydrogel sensor for the monitoring of glucose.…”

Section: Introductionmentioning

confidence: 99%

Construction of a Novel Photoresponsive Supramolecular Fluorescent Hydrogel through Host‐Guest Interaction between β‐Cyclodextrin and Azobenzene

et al. 2020

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In the present work, we constructed a novel photoresponsive supramolecular fluorescent hydrogel through host-guest interaction between β-cyclodextrin group in polymer 1 and azobenzene group in polymer 2. Under different external irradiations, the fluorescent hydrogel exhibited different inten-sities to the photo-isomerisation of azobenzene. Light is an ideal stimulus because of its simple operation and nonintroduction of additional impurities. Therefore, this photoresponsive supramolecular hydrogel can serve as an excellent strategy for designing more practical materials.

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Synthesis of a glucose oxidase-conjugated, polyacrylamide-based, fluorescent hydrogel for a reusable, ratiometric glucose sensor

Abstract: New emission color-changeable hydrogels containing glucose oxidase were synthesized to be used in glucose sensing.

Cited by 22 publications

References 54 publications

Progress in hydrogels for sensing applications: a review

Progress in hydrogels for sensing applications: a review

Honey-inspired antimicrobial hydrogels resist bacterial colonization through twin synergistic mechanisms

Construction of a Novel Photoresponsive Supramolecular Fluorescent Hydrogel through Host‐Guest Interaction between β‐Cyclodextrin and Azobenzene

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