Fluoride Distribution in Sound and Carious Root Tissues of Human Teeth

Shu, M.; Pearce, E.I.F.; Sissons, C.H.; Coote, G.E.; Miller, James H.

doi:10.1159/000016459

Cited by 12 publications

(6 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Residents in the unfluoridated area presented 21% more root caries per person than those with root caries from the fluoridated area. A proton probe was employed to provide a quantitative estimation of fluoride concentration in carious root tissues from subjects consuming water containing 1 ppm fluoride [Shu et al, 1998]. They reported that in large lesions with extensive cavitation fluoride was concentrated in the outer edge of the lesion and was significantly higher (1,800-4,100 ppm) than in adjacent sound inner dentine (190-290 ppm).…”

Section: Use Of Dentifrices Containing Fluoride For the Management Ofmentioning

confidence: 99%

Reversal of Primary Root Caries Using a Dentifrice with a High Fluoride Content

Lynch¹,

Baysan²

2001

Caries Res

View full text Add to dashboard Cite

Root caries is a widespread problem and can be quite serious in older populations. The restoration of root carious lesions is often difficult. Compared to enamel caries, there has been limited research into the pharmaceutical management of primary root caries lesions (PRCLs), and many of these studies have been carried out in vitro, with limited numbers of clinical trials. Fluoride is presently a cornerstone in dentifrice formulations for cost-effective and anticaries therapy. It is generally accepted that fluoride ions promote remineralization of tooth substances and reduce the rate of demineralization. The use of a dentifrice with a high fluoride content may be considered to reverse PRCLs, since more fluoride is required for the remineralization of roots than for enamel. This paper reviews the effects of dentifrices with high fluoride contents on the management of root caries.

show abstract

Section: Use Of Dentifrices Containing Fluoride For the Management Ofmentioning

confidence: 99%

Reversal of Primary Root Caries Using a Dentifrice with a High Fluoride Content

Lynch¹,

Baysan²

2001

Caries Res

View full text Add to dashboard Cite

show abstract

“…Fluoride incorporation into tooth mineral may result also in reduced demineralization since fluoroapatite is somewhat less acid‐soluble than is hydroxylapatite. However, it is well know that the fluoride important for caries reduction is that in plaque, although it appears that fluoride from dissolved enamel or from fluoride‐containing varnishes may enter into plaque and become part of the total [97,100]. Moreover, this released fluoride can inhibit acid production by plaque bacteria [44].…”

Section: Introductionmentioning

confidence: 99%

Fluoride and organic weak acids as modulators of microbial physiology

2003

View full text Add to dashboard Cite

Fluoride is widely used as an anticaries agent in drinking water and a variety of other vehicles. This use has resulted in major health benefits. However, there are still open questions regarding the mechanisms of anticaries action and the importance of antimicrobial effects in caries reduction. Fluoride acts in multiple ways to affect the metabolism of cariogenic and other bacteria in the mouth. F(-)/HF can bind directly to many enzymes, for example, heme-containing enzymes or other metalloenzymes, to modulate metabolism. Fluoride is able also to form complexes with metals such as aluminum or beryllium, and the complexes, notably AlF(4)(-) and BeF(3)(-).H(2)O, can mimic phosphate with either positive or negative effects on a variety of enzymes and regulatory phosphatases. The fluoride action that appears to be most important for glycolytic inhibition at low pH in dental plaque bacteria derives from its weak-acid properties (pK(a)=3.15) and the capacity of HF to act as a transmembrane proton conductor. Since many of the actions of fluoride are related to its weak-acid character, it is reasonable to compare fluoride action to those of organic weak acids, including metabolic acids, food preservatives, non-steroidal anti-inflammatory agents and fatty acids, all of which act to de-energize the cell membrane by discharging DeltapH. Moreover, with the realization that the biofilm state is the common lifestyle for most microorganisms in nature, there is need to consider interactions of fluoride and organic weak acids with biofilm communities. Hopefully, this review will stimulate interest in the antimicrobial effects of fluoride or other weak acids and lead to more effective use of the agents for disease control and other applications.

show abstract

“…6 Fluoride-and CHX-containing antibacterial agents can be promising for the remineralization of initial root caries. However, such varnishes can penetrate demineralized root dentin only up to 40% of the total lesion depth, due to their hydrophobic nature.…”

Section: Discussionmentioning

confidence: 99%

“…[3][4][5] Fluoride inhibits root caries, as it does coronal caries, even though the tissues initially affected are quite different. 6 Several in situ and in vivo studies demonstrated the cariostatic effect of topically applied fluorides on initial root surface lesions. [7][8] Chlorhexidine (CHX)-containing products are noteworthy, because of their ability to reduce pathogens from the immediate environment and possibly from carious dentin and soft tissues.…”

Section: Introductionmentioning

confidence: 99%

Effect of Antibacterial Varnishes Applied to Root Dentin on Shear Bond Strength of Tooth-colored Restorative Materials

Korkmaz¹,

Başeren²

2008

Operative Dentistry

View full text Add to dashboard Cite

This study investigated the effect of certain varnishes on the bond strength of different tooth-colored restorative materials applied to root dentin. One-hundred and eighty tooth slabs, including mesial and distal surfaces, were attained through dividing the teeth, then embedding them in methylmethacrylate. The root surfaces were ground flat through cementum, exposing the dentin. The samples were then randomly divided into three main groups: Group 1: Cervitec; Group 2: Fluor Protector and Group 3: No applications (control). Cervitec and Fluor Protector were applied to the root dentin surfaces according to the manufacturer's instructions. All the samples were kept in artificial saliva for six months. Each main group was subdivided into five groups of 12 teeth each: Group A: Flowable Resin Composite (Grandio Flow); Group B: Microhybrid Resin Composite (Artemis); Group C: Polyacid Modified Resin Composite (Dyract Extra); Group D: Resin Modified Glass Ionomer Cement (Vitremer) and Group E: Conventional Glass-Ionomer Cement (Ionofil Molar). Restorative materials were applied to the root dentin surfaces using a cylindrical mold. After thermocycling (1000 cycles, 5 degrees C/55 degrees C, dwell time 30 seconds), the shear bond strength of the restored samples was determined by a universal testing machine (Zwick Test Machine, Zwick GmbH & Co, Ulm, Germany) at a 5 mm/minute crosshead speed. Failure mode was determined under a stereomicroscope. The data were evaluated statistically by using one-way Analysis of Variance and Duncan tests (p< or =0.05). In the fluoride varnish group, all of the restorative materials except for Ionofil Molar, showed lower bond strengths when compared to the control group (p<0.05). In the Cervitec group, Artemis and Dyract Extra showed lower bond strengths; whereas, Ionofil Molar showed a higher bond strength than the control group (p<0.05). The highest percentage of cohesive fracture was observed in Artemis and Dyract Extra in the control group.

show abstract

Fluoride Distribution in Sound and Carious Root Tissues of Human Teeth

Cited by 12 publications

References 45 publications

Reversal of Primary Root Caries Using a Dentifrice with a High Fluoride Content

Reversal of Primary Root Caries Using a Dentifrice with a High Fluoride Content

Fluoride and organic weak acids as modulators of microbial physiology

Effect of Antibacterial Varnishes Applied to Root Dentin on Shear Bond Strength of Tooth-colored Restorative Materials

Contact Info

Product

Resources

About