Fluorinated Montmorillonite and 3YSZ as the Inorganic Fillers in Fluoride-Releasing and Rechargeable Dental Composition Resin

Abstract

Dental caries (tooth decay) is the most frequent oral disease in humans. Filling cavities with a dental restorative material is the most common treatment, and glass ionomer cements are the main fluoride ion release restorative materials. The goal of this study was to develop a restorative compound with superior fluoride ion release and recharge abilities. Previously developed fluorinated bentolite and hydrophobized 3YSZ were used as two different inorganic fillers mixed in a bisphenol A-glycidyl methacrylate (Bis-GMA) matrix. XRD, FTIR, and TGA were used to determine the hydrophobic modification of these two inorganic fillers. In mechanical tests, including diameter tensile strength, flexural strength, and wear resistance, the developed composite resin was significantly superior to the commercial control. A WST-1 assay was used to confirm that the material displayed good biocompatibility. Furthermore, the simulation of the oral environment confirmed that the composite resin had good fluoride ion release and reloading abilities. Thus, the composite resin developed in this study may reduce secondary caries and provide a new choice for future clinical treatments.

Evaluation of Novel Tranexamic Acid/Montmorillonite Intercalation Composite, as a New Type of Hemostatic Material

“…Analysis showed that this was caused by the stretching vibration of the carbonyl group at 1719 cm −1 and the stretching vibration of C-H on saturated carbon at 2945 cm −1 . Both the carbonyl group and the C-H group are groups of TXA, indicating that TXA reacted with montmorillonite to form a new product [37][38][39]. The interlayer of montmorillonite was combined by van der Waals force, and the many metal cations and hydroxyl hydrophilic groups in the montmorillonite cell thus showed strong hydrophilicity, and water molecules could enter the interlayer, causing the interlayer spacing (d001) to increase, resulting in the expansion of montmorillonite.…”

Montmorillonite in dentistry: a review of advances in research and potential clinical applications

“…Therefore, fluorinated MMT (F-MMT) could act as a filler for the polymer matrix and as a source of fluoride ions for targeted release [85][86][87]. Recent studies have successfully demonstrated that F-MMT incorporated into a resin matrix (acrylamide) can achieve a desirable sustained release of fluoride and dual fluoride release mechanism [17,50]. The material developed showed great potential for application in dentistry as a pit and fissure sealant.…”

“…The lattice structure of the alternating tetrahedral sheets and octahedron sheets is shown in figure 1(B). Outside of dentistry, MMT has attracted interest in various fields, including reinforcing ceramics, improving polymer composites, as a crucial organic catalyst, and in medical and pharmaceutical applications [17,18].…”

Research on the Mechanical Properties, Fluoride and Monomer Release of a New Experimental Flowable Giomer in Comparison to Three Commercial Flowable Giomers

“…This material is proven to have anti-plaque effect, reducing the adherence of harmful bacteria to the tooth structure, is adequate for the treatment of hypersensitivity and non-cytotoxic to human teeth [6]. Appling PRG-technology to the filler in resin based composite materials gives them bioactive properties through fluoride release and recharge, similar to traditional glass-ionomers, but maintaining in the same time physical and esthetical properties of the composites [7,8].…”