Fluorinated polyphosphazene polyelectrolytes

Abstract

Polyphosphazene polyelectrolytes containing various amounts of hydrophobic fluorinated moieties and ionic carboxylic acid groups were synthesized. Polymer compositions and molecular weights were characterized by NMR and gel permeation chromatography. Interestingly, poly[(carboxylatophenoxy)(trifluoroethoxy)phosphazene] containing 60 mol % fluorinated groups was found to be soluble in aqueous solutions. The behavior of fluorinated polyelectrolytes in reactions of ionic complexation with multivalent and monovalent salts was studied in aqueous solutions and ethanolwater mixtures. Such reactions led to the formation of ionotropic hydrogels under mild conditions and, thus, are of importance to the development of microencapsulation processes and controlled release formulations. All of the synthesized polymers underwent phase separation in the presence of multivalent ionic crosslinkers, such as spermine and calcium chloride. This included a water-soluble polyelectrolyte containing 40 mol % ionic groups and hydrophobic polymer with only 3 mol % carboxylic acid groups.

Inorganic and organometallic polymers

“…62 The synthesis and properties of polyphosphazene polyelectrolytes have been the subject of several additional studies. [63][64][65] ð9Þ A monotelechelic polyphosphazene, prepared using the living cationic polymerization of phosphoranimines, was attached to an amine core 20 to afford novel polyphosphazene dendrimers 21. 66 These novel dendrimers may be further functionalized by nucleophilic substitution of the P-Cl bonds of the phosphazene chain with hydrophilic segments (i.e.…”

Solution and diffusion properties of organic sulfur in poly[bis(phenoxy)phosphazene] by inverse gas chromatography

“…46 Polyphosphazenes (POPs), which are polymers with phospho-47 rus and nitrogen backbone and organic side groups. The chemical 48 and physical properties of POPs could be easily tailored by the 49 incorporation of various pendant groups [7][8][9][10][11]. In our previous 50 work, poly[bis(phenoxy)phosphazene] (PBPP) was synthesized 51 and investigated as pervaporation desulfurization membrane 52 material.…”

Polyphosphazenes for Biology and Medicine: Current Status and Future Prospects

“…Two examples are biodegradable shape-memory polymer as an intelligent suture for wound closure, and insertion of bulky implants into the human body in compressed form through a small incision, with the implants turning into their application-relevant shape within the body [25,26]. Other areas are biodegradable slow-release coating for stents, where biological parameters have to be blended with intrinsic polymer characteristics [27][28][29], or biocompatible fluorinated coatings, which can be based on multilayer fluorinated systems [30].…”