Polyphosphazenes for Biology and Medicine: Current Status and Future Prospects

Synthesis, structural characterization and anti-carcinogenic activity of new cyclotriphosphazenes containing dioxybiphenyl and chalcone groups

“…The phosphazene derivatives have various physical and biological properties, for example liquid crystals [2,3], electrical conductivity [4], flame retardants [5][6][7], electrolytes for rechargeable batteries [8], fire resistant materials [9], dielectric properties [10], biomedical applications [11,12], antimicrobial, antibacterial [13][14][15][16][17][18], anti-leukemic [19] and strong anti-tumor activity [20][21][22][23][24][25][26][27].…”

Microneedles with Intrinsic Immunoadjuvant Properties: Microfabrication, Protein Stability, and Modulated Release

“…Polyphosphazenes, synthetic macromolecules with phosphorus-nitrogen backbone and organic side groups, represent an increasingly important class of biomedical polymers (11). In particular, Poly[di(carboxylatophenoxy)phosphazene], PCPP (Fig.…”

Biodegradable polymeric nanomaterials

“…Polyphosphazenes are flexible polymers with good processability and they may participate in noncovalent bonding which in-turn may create new interfacial interactions with biological systems. Consequently, the unique structural diversity of biodegradable polyphosphazenes associated with their potential multifunctionality should allow for the design of nanomaterials with superior biological characteristics [25]. Polyphosphazenes-based nanofibres and nanoparticles show significant promise in drug delivery and tissue engineering applications.…”