Flush preservation

Collins, Geoffrey M.

doi:10.1007/978-94-011-6267-8_22

Cited by 3 publications

(2 citation statements)

References 66 publications

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“…In situ perfusion with Collin's solution (n = 28) was performed until January, 1988. Since that time, the University of Wisconsin solution has been employed (n = 21) (15,16). Each donor organ was brought to the recipient operating room, and the size disparity was assessed after recipient hepatectomy had begun and the hepatic fossa was visualized directly.…”

Section: Patient Selectionmentioning

confidence: 99%

Reduced–Size Orthotopic Liver Transplantation: Use in the Management of Children With Chronic Liver Disease

et al. 1989

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Reducing the size of a liver for use in a recipient smaller than the donor is one way to reduce mortality before orthotopic liver transplantation in children because of the scarcity of pediatric organ donors. In this report, we review the results of this approach over the past 2 years, during which we have used reduced-size orthotopic liver transplantation routinely in small children. Forty-nine children underwent orthotopic liver transplantation between September, 1986, and October, 1988; orthotopic liver transplantation with a whole organ (full-size orthotopic liver transplantation) was performed in 36 children, whereas 13 patients received reduced-size orthotopic liver transplantation. In two pairs of patients, the reduced grafts were obtained from single donors, using a "split-liver" procedure. All grafts were implanted in the orthotopic position following total recipient hepatectomy. The preoperative diagnostic categories were not significantly different between groups. Patients receiving reduced-size orthotopic liver transplantation were younger (1.6 +/- 1.5 vs. 4.4 +/- 4.6 years), and a higher percentage were in the intensive care unit prior to transplant (31 vs. 9%). Thirty of 36 (82%) patients receiving full-size orthotopic liver transplantation and 10 of 13 (77%) patients receiving reduced-size orthotopic liver transplantation are alive 3 to 27 months after transplantation. The rates of retransplantation were 24% for full-size orthotopic liver transplantation and 15% for reduced-size orthotopic liver transplantation. Despite the greater complexity of reduced-size orthotopic liver transplantation and the higher frequency of critically ill recipients selected for the procedure, the results of reduced-size orthotopic liver transplantation are comparable with full-size orthotopic liver transplantation.(ABSTRACT TRUNCATED AT 250 WORDS)

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Section: Patient Selectionmentioning

confidence: 99%

Reduced–Size Orthotopic Liver Transplantation: Use in the Management of Children With Chronic Liver Disease

et al. 1989

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“…The PHC was the first local historical commission with jurisdiction over an entire metropolitan area. 45 It was a seven-member advisory body charged with regulating the demolition of historic structures, designating and reviewing alterations to individual buildings, and generally "preserving all that was of historical value to the city." 46 By the time it was established, the preservation of Philadelphia's Colonial-era heritage, centered on Independence Hall, was well under way.…”

mentioning

confidence: 99%

Historic Preservation’s Urban Renewal Roots

Ryberg

2012

Journal of Urban History

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This article analyzes the intersection of historic preservation and city planning in post-WWII Philadelphia. Using over forty-five area plans, the city’s 1960 Comprehensive Plan, and contemporary media reports, the article explores the relationship between the Philadelphia City Planning Commission and the Philadelphia Historical Commission, the first citywide preservation commission in the United States. The article debunks the conventional wisdom that midcentury clearance and redevelopment strategies galvanized the historic preservation movement. Rather, the Philadelphia case demonstrates that the preservation community adopted a narrow definition of “historic,” while a rehabilitation ethic permeated the Planning Commission’s conservative approach to renewal, ultimately resulting in the retention of existing buildings, the integration of older fabric with modern infill, and the implicit preservation of much of the city’s residential built environment.

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A new preservation solution for storage of corneas at low temperatures

Taylor

Hunt

1985

Current Eye Research

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Cryopreservation methods are only rarely used today for storing donor material for use in penetrating keratoplasty. There remains, however, a continuing need for a reliable technique for the long-term preservation of corneas. As a first step in developing an improved method of corneal cryopreservation we have studied the composition of the preservation medium. On the basis of experiments with other tissues a new solution (designated CPTES) has been formulated, containing concentrations of potassium, sodium and chloride similar to normal intracellular levels, in order to restrict the ionic imbalances that occur when temperature is reduced and ionic pumps switched off. An impermeant anion was included to reduce cellular swelling during low temperature storage. Integrity of the corneal endothelium was demonstrated following exposure to CPTES medium at 0 degree C: control of corneal hydration and the presence of an active bicarbonate - dependent pump were demonstrated by specular microscopy; normal ultrastructure of the endothelial layer was revealed by electron microscopy. The incorporation and removal of 1M dimethyl sulphoxide (Me2SO) is tolerated in corneas bathed in CPTES medium at 0 degree C, again with retention of endothelial structural and functional integrity. CPTES is proposed as a medium which will help to control osmotic and ionic disturbances during experimental procedures designed to improve methods of corneal preservation both above and below 0 degree C.

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Flush preservation

Cited by 3 publications

References 66 publications

Reduced–Size Orthotopic Liver Transplantation: Use in the Management of Children With Chronic Liver Disease

Reduced–Size Orthotopic Liver Transplantation: Use in the Management of Children With Chronic Liver Disease

Historic Preservation’s Urban Renewal Roots

A new preservation solution for storage of corneas at low temperatures

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