FNA diagnosis of malignant melanoma-recurrent and metastatic disease

Abstract

We present a case of a 60-year-old woman with multiple right axillary swellings. Patient had a history of lump with pigmentation over back for which she was operated upon. There was also a nodule over resected scar on back. A final diagnosis of malignant melanoma (recurrent and metastatic to axillary lymph nodes) was rendered with the help of fine-needle aspiration cytology (FNAC). Malignant melanomas are the most lethal of cancers of the skin and are notorious for the great variability of cytological presentation. We discuss the role of FNAC in early diagnosis and prognostication of recurrent and metastatic disease.

Cervical lymph node metastasis of ovarian dysgerminoma: A case report with fine needle aspiration cytology

“…Lymphoma is generally characterized by single medium to large cells, irregular nuclei, and high cellularity . Cytologically, melanoma cells have inclusion‐like prominent nucleoli, and usually melanin pigments are seen . Lymph nodes of metastatic ovarian carcinomas show cohesive epithelial clusters .…”

“…9 Cytologically, melanoma cells have inclusion-like prominent nucleoli, and usually melanin pigments are seen. 10 Lymph nodes of metastatic ovarian carcinomas show cohesive epithelial clusters. 11 However, these differential diagnoses are difficult to distinguish without definitive immunocytochemistry.…”