Foamy gland microcarcinoma in needle prostatic biopsy

Foamy gland adenocarcinoma of the prostate: incidence, Gleason grade, and early clinical outcome

“…Based on the few cases thus far reported in the literature [1,2,[5][6][7][8]12,13], foamy gland adenocarcinoma of the prostate might be considered an uncommon variant of usual acinar adenocarcinoma; but incidence data have not been previously gathered. In the 2 separate series we report here, foamy gland carcinoma, as a component of usual acinar adenocarcinoma, is present in 15% to 23% of clinically organ-confined prostatic carcinomas.…”

“…This variant is characterized by abundant xanthomatous cytoplasm and often by pyknotic nuclei [1][2][3][4][5]. The typical cytologic features of acinar adenocarcinoma, such as nuclear enlargement and prominent nucleoli, are frequently absent, making this variant more difficult to diagnose, especially on needle biopsy [3,4,[6][7][8]. The usual Gleason grade for foamy gland adenocarcinoma has often been described to be 3 + 3 = 6 [1,2,9,10].…”

Pseudohyperplastic prostate carcinoma: histologic patterns and differential diagnosis

“…The original diagnosis for 20 of the cases received in consult included hyperplastic nodules, lowgrade prostate adenocarcinoma [4,8], prostate adenosis [8][9][10][11], diffuse adenosis of the peripheral zone [12,13], benign cystic glands vs atrophic carcinoma [14][15][16][17][18], PIN [19,20], atypical small acinar proliferation [21,22], and xanthomatous carcinoma [23][24][25][26].…”

Expression and significance of cortactin and HDAC6 in human prostatic foamy gland carcinoma

“…Till now, only limited literature has been published about the clinicopathologic attributes and prognosis of this carcinoma with Gleason score of 7 or higher (Arista‐Nasr et al . ; Zhao & Epstein ; Wolters et al . ; Hudson et al .…”