Focal hyalinization during experimental tooth movement in beagle dogs

Böhl, Martina von; Maltha, Jaap C.; Hoff, Johannes W. Von den; Kuijpers-Jagtman, Anne Marie

doi:10.1016/j.ajodo.2003.08.023

Cited by 119 publications

(50 citation statements)

References 14 publications

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“…These results reveal important clinical implications for orthodontics and provide evidence for the utilization of light continuous force in orthodontics at the cellular level [44], since light continuous forces induce relatively longer lasting levels of cytokines, which are necessary for continuous periodontal remodeling. Heavy decaying force may increase the risk of root resorption and PDL hyalinization [45,46], and may also tend to induce acute up-and-downs in cytokine levels, which may cause undesirable tissue reactions and need for more re-activations.…”

Section: Discussionmentioning

confidence: 99%

Cytokines in crevicular fluid and orthodontic force: a systematic review

Allgayer

Menezes

Rinaldi

2017

Rev. Odonto Ciênc. (Online)

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OBJECTIVE: This paper aimed to analyze studies in the literature addressing the role of cytokines in the gingival crevicular fluid (GCF) in the orthodontic treatment. METHODS: Several databases were surveyed using both MESH terms and free terms. Additional studies were obtained by reference tracking. This review was registered in PROSPERO, and the procedures foreseen by its statement were followed. Data were obtained from the included studies addressing the orthodontic mechanics, GCF sampling/handling methods, and cytokine measurements. Clinical studies written in English were browsed. Papers were selected by one reviewer and checked by a second investigator. RESULTS: A total of 115 articles were identified, among which 25 were selected for detailed analysis. Common drawbacks consisted mainly of inadequacies in the study design (e.g. short duration and small number of study subjects). The most consistent result was a peak of cytokine levels at 1 d. Associations were observed between prostaglandin E2 (PGE2) and interleukin-1β (IL-1β) and pain, velocity of tooth movement, and treatment mechanics. Interleukin-1b and PGE2 showed different patterns of up-regulation, with IL-1β being more responsive to mechanical stress and PGE2 more responsive to synergistic regulation of IL-1β and mechanical force. The results support the use of light continuous forces for orthodontic treatment. CONCLUSION: There was a tendency of maintenance of relatively high IL-1β levels for longer periods with the use of light continuous forces, which might decrease the frequency of activation. These outcomes provide evidence at the cellular level for the utilization of light continuous forces.Key words: Systematic review; Orthodontics, corrective; Gingival Crevicular Fluid (GCF); Interleukin; T Cells.Papel das citocinas presentes no fluido crevicular durante o tratamento ortodôntico: uma revisão sistemática REsUMO OBJETIVO: Este artigo teve como objetivo analisar estudos na literatura abordando o papel das citocinas no Líquido do Sulco Gengival no tratamento ortodôntico. MéTODOS: Várias bases de dados foram pesquisadas usando termos MESH e termos livres. Estudos adicionais foram obtidos por rastreamento de referência. Esta revisão foi registrada no PROSPERO, e os procedimentos previstos por sua declaração foram seguidos. Os dados foram obtidos dos estudos incluídos sobre a mecânica ortodôntica, métodos de amostragem / manuseio de Líquido do Sulco Gengival e medições de citoquinas. Estudos clínicos escritos em inglês foram pesquisados. Os trabalhos foram selecionados por um revisor e verificados por um segundo investigador. RESULTADOS: Foram identificados 115 artigos, dentre os quais 25 foram selecionados para análise detalhada. As desvantagens comuns consistiram principalmente em insuficiências no design do estudo (por exemplo, curta duração e pequeno número de sujeitos do estudo). O resultado mais consistente foi um pico de níveis de citocinas a 1 d. Foram observadas associações entre prostaglandina E2 (PGE2) e interleucina-1β (IL-1β) ...

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Section: Discussionmentioning

confidence: 99%

Cytokines in crevicular fluid and orthodontic force: a systematic review

Allgayer

Menezes

Rinaldi

2017

Rev. Odonto Ciênc. (Online)

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“…Hyalinization occurs in the PDL and is proposed to indicate hyaline-like tissue formation that no longer has normal tissue architecture. Macrophages are responsible for removing the hyalinized tissues prior to which little tooth movement occurs [55]. Extracellular matrix and cell distortion causes structural and functional changes in cell membrane, and cytoskeletal proteins.…”

Section: Pdl and Alveolar Bone Resorption And Remodelingmentioning

confidence: 99%

Periodontal Ligament and Alveolar Bone in Health and Adaptation: Tooth Movement

Jiang¹,

Guo²,

Chen³

et al. 2015

Frontiers of Oral Biology

142

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The periodontal ligament (PDL) and alveolar bone are two critical tissues for understanding orthodontic tooth movement. The current literature is replete with descriptive studies of multiple cell types and their matrices in the PDL and alveolar bone, but is deficient with how stem/progenitor cells differentiate into PDL and alveolar bone cells. Can one type of orthodontic force with a specific magnitude and frequency preferably activate osteoblasts, whereas another force type activates osteoclasts? This chapter will discuss the biology of not only mature cells and their matrices in the periodontal ligament and alveolar bone, but also stem/progenitor cells that differentiate into fibroblasts, osteoblasts and osteoclasts. Key advances in tooth movement rely on further understanding of osteoblast and fibroblast differentiation from mesenchymal stem/progenitor cells, and osteoclastogenesis from the hematopoietic/monocyte lineage.

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“…RAP was explained as a temporary stage of localized soft and hard-tissue remodeling that resulted in rebuilding of the injured sites to a normal state through recruitment of osteoclasts and osteoblasts via local intercellular mediator mechanisms involving precursors, supporting cells, blood capillaries and lymph [10]. This accelerated remodeling is influenced by bone density and the hyalinization of the periodontal ligament (PDL) [11-14]. …”

Section: Historical Backgroundmentioning

confidence: 99%

Corticotomy-Assisted Orthodontic Treatment: Review

Hassan

Al-Fraidi²,

Al-Saeed³

2010

TODENTJ

114

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Corticotomy-assisted orthodontic treatment is an established and efficient orthodontic technique that has recently been studied in a number of publications. It has gradually gained popularity as an adjunct treatment option for the orthodontic treatment of adults. It involves selective alveolar decortication in the form of decortication lines and dots performed around the teeth that are to be moved. It is done to induce a state of increased tissue turnover and a transient osteopenia, which is followed by a faster rate of orthodontic tooth movement. This technique has several advantages, including faster tooth movement, shorter treatment time, safer expansion of constricted arches, enhanced post-orthodontic treatment stability and extended envelope of tooth movement. The aim of this article is to present a comprehensive review of the literature, including historical background, contemporary clinical techniques, indications, contraindications, complications and side effects.

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Focal hyalinization during experimental tooth movement in beagle dogs

Cited by 119 publications

References 14 publications

Cytokines in crevicular fluid and orthodontic force: a systematic review

Cytokines in crevicular fluid and orthodontic force: a systematic review

Periodontal Ligament and Alveolar Bone in Health and Adaptation: Tooth Movement

Corticotomy-Assisted Orthodontic Treatment: Review

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