A non-contact method for efficient, non-invasive excitation of mechanical waves in soft media is proposed, in which we focus an ultrasound (US) signal through air onto the surface of a medium under study. The US wave reflected from the air/medium interface provides radiation force to the medium surface that launches a transient mechanical wave in the transverse (lateral) direction. The type of mechanical wave is determined by boundary conditions. To prove this concept, a homemade 1 MHz piezo-ceramic transducer with a matching layer to air sends a chirped US signal centered at 1 MHz to a 1.6 mm thick gelatin phantom mimicking soft biological tissue. A phasesensitive (PhS)-optical coherence tomography system is used to track/image the mechanical wave. The reconstructed transient displacement of the mechanical wave in space and time demonstrates highly efficient generation, thus offering great promise for non-contact, non-invasive characterization of soft media, in general, and for elasticity measurements in delicate soft tissues and organs in bio-medicine, in particular. Published by AIP Publishing. [http://dx.doi.org/10.1063/1.4959827] Acoustic radiation force (ARF) is commonly used in ultrasound (US)-based elastography to remotely generate shear waves deep within tissue. 1-3 Detection of shear waves can be performed with a conventional ultrasound (US) imaging probe or with another imaging method, e.g., optical coherence tomography (OCT). The combination of ARF with high frame rate OCT can produce quantitative crosssectional maps of the shear modulus in soft tissues. 4 For many clinical applications, however, a totally non-contact system for generation/detection of mechanical waves is desirable and, in some cases (for instance, the eye), is necessary. OCT is an ideal approach for these applications if an efficient and robust non-contact generation technology can be developed.Generation of mechanical waves with an air puff was used in Ref. 5 to produce very narrow bandwidth displacements in the cornea, which may not be able to characterize corneal elasticity at the spatial resolution required for clinical decision making. Our group has recently demonstrated non-contact generation using absorption of pulsed UV laser light. 6 Although UV generation can provide the bandwidth required for high spatial resolution maps of corneal elasticity, it is not clear at this point whether the required UV energy levels will meet the safety requirement for routine clinical use.Here we propose a fully non-contact and non-invasive US technique to create efficient localized wideband mechanical waves in soft tissue. The method utilizes US launched with an air-coupled transducer (i.e., through air) to the air/ medium interface. The US wave reflected from this interface provides radiation force to the medium surface, which induces a transient displacement at that surface, ultimately generating a propagating shear/guided/interface/Lamb wave (wave type determined by boundary conditions). We will call this the mechanical wave to maintain ge...