Foeniculum vulgare therapy in irritable bowel syndrome

Amjad, Hassan; Jafary, H A

doi:10.1016/s0002-9270(00)01425-8

Cited by 3 publications

(2 citation statements)

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“…Studies in vivo with seeds oil emulsion eliminated infantile colic (Alexandrovich et al 2003). Study with carrying patients of irritable bowel syndrome showed that the extract of seeds of F. vulgare has a spasmodic effect, improving the quality of life of these people (Amjad 2000).…”

Section: Resultsmentioning

confidence: 99%

Indigenous traditional medicine: in vitro anti-giardial activity of plants used in the treatment of diarrhea

et al. 2009

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The ethnopharmacology for treatment of parasitic infections facilitates and directs the search for new chemical entities. In this direction, this study evaluated the cytotoxicity in vitro, against trophozoites of Giardia lamblia, of aqueous extracts of leaves Achyrocline satureioides (Lam.) DC., barks of Eugenia uniflora L., aerial parts of Foeniculum vulgare Miller, and barks of Psidium guajava L. These plants are traditionally used for the treatment of diarrhea by the indigenous population Mbyá-Guarani, located at the Lomba do Pinheiro, Porto Alegre, Rio Grande do Sul, Brazil. The in vitro susceptibility qualitative analysis of G. lamblia to aqueous extracts was performed in serial dilutions from 2.5 to 0.02 mg/mL. Results revealed the minimal inhibitory concentrations: 0.313 mg/mL for A. satureioides and E. uniflora, 0.02 mg/mL for P. guajava, and F. vulgare did not present any cytotoxic effect. Quantitative assays of viable trophozoites, showed that A. satureioides presented the highest cytotoxic effect (93.5%), followed by P. guajava (82.2%), and E. uniflora (67.3%). Indigenous Guarani use mainly A. satureioides for the treatment of diarrhea, revealing the conformity with results obtained in vitro. Bioguided assays are necessary to identify the compounds responsible for the activity of the aqueous extract of A. satureioides.

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Section: Resultsmentioning

confidence: 99%

Indigenous traditional medicine: in vitro anti-giardial activity of plants used in the treatment of diarrhea

et al. 2009

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“…Anethole, the major component of fennel oil seeds, is chemically similar to the neurotransmitter dopamine and has a relaxant effect on intestinal smooth muscle, isolated rat uterus [ 120 ] and guinea pig trachea rings [ 121 ]. In a pilot study on IBS patients, the fennel reduced crampiform abdominal pain, a mechanism likely mediated by the anethole-dependent relaxation of intestinal smooth muscle [ 122 ]. The combination of curcumin-fennel essential oil has been recently used by our group and has improved symptoms and quality of life in IBS patients [ 123 ].…”

Section: Common Dietary Targets In Treating Ibsmentioning

confidence: 99%

Irritable bowel syndrome and diet

Portincasa

Bonfrate

Bari

et al. 2017

Gastroenterology Report

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Irritable bowel syndrome (IBS) is a chronic functional disorder of the gastrointestinal tract and is one of the most commonly diagnosed gastrointestinal diseases. The impact of IBS on the general population is large due to its high prevalence, suboptimal medical treatments and significant economic burden. The pathophysiology of IBS is complex and treatments are often symptom-specific. The most common therapeutic approaches for IBS include education and reassurance, lifestyles (especially nutrition-based interventions), peripherally acting medications (which typically target motility), centrally acting medications (which target visceral hypersensitivity and pain) and psychological interventions (which aim to reduce the effects of stress or symptom-specific anxiety). A beneficial dietary approach might include the following measures: a diet low in fermentable oligo-,di- and monosaccharides and polyols (FODMAPs), limitation or exclusion of gas-producing foods and/or lactose and gluten and fiber supplementation in selected cases. New therapeutic agents, namely nutraceutics, are also an interesting option in the management of IBS patients. This paper will focus on available dietary interventions for IBS and will review the evidence for nutrition-based therapies.

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Dados químicos e farmacológicos sobre as plantas utilizadas como medicinais pela comunidade do bairro Ponta Grossa, Porto Alegre, Rio Grande do Sul

Vendruscolo¹,

Rates²,

Mentz³

2005

Rev. bras. farmacogn.

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Para estas espécies foi realizada uma revisão bibliográfi ca, buscando estudos sobre sua constituição química e atividade farmacológica. Para todas as espécies foram encontrados dados químicos e para nove delas dados de atividade farmacológica. Foram encontrados estudos clínicos para quatro espécies e usos terapêuticos aprovados por organismos internacionais para três espécies. Efeitos adversos foram encontrados, na literatura, para cinco das dez espécies pesquisadas e para seis destas, o uso durante a gestação é desaconselhado.Unitermos: Etnobotânica, plantas medicinais, farmacologia.ABSTRACT: "Chemical and pharmacologic data on medicinal plants used by the community of the Ponta Grossa neighborhood, Porto Alegre, Rio Grande do Sul, Brazil". The ten most important species among all plants used as medicinal by the residents and Communitary Agents of Health from the Family Health Offi ce of Ponta Grossa neighborhood, Porto Alegre, Rio Grande do Sul, Brazil were selected. A bibliographical review for these species was accomplished, fi nding studies about the chemical constitution for all species and some pharmacologic activity for nine of them. Clinical studies for four species and therapeutic uses approved by international organisms for three species were found. It was verifi ed that according to the literature, adverse effects for fi ve of the ten researched species and for six of these the use is dissuaded during the gestation.Keywords: Ethnobotany, medicinal plants, pharmacology. INTRODUÇÃONo Brasil, a possibilidade de implementação da fi toterapia no sistema público de saúde vem sendo considerada desde 1988 (CIPLAN) e faz parte das diretrizes da I Conferência Nacional de Assistência Farmacêutica (CNMAF, 2003). A partir de então, várias inicativas pontuais para estabelecer a fi toterapia na rede pública de sáude vêm ocorrendo, com destaque para o Programa de Fitoterapia do Ceará, alicerçado no Projeto Farmácias Vivas, idealizado pelo Prof. Francisco José de Abreu Matos (Matos et al., 2001). No entanto, para a maioria das plantas nativas não existem estudos científi cos e o uso no Brasil é baseado principalmente na tradicionalidade. A OMS reconhece a importância do uso tradicional, mas para a utilização de uma planta com fi nalidade terapêutica, em nível de saúde pública, é fundamental o estabelecimento de sua segurança, efi cácia e garantia de qualidade das preparações (Lapa et al., 2003; WHO, 2002;Rates, 2001). O uso inadequado destes recursos terapêuticos pode originar efeitos adversos retardados e/ou assintomáticos, interações medicamentosas ainda não estudadas e difi cilmente reconhecidas, além de retardar o diagnóstico e tratamento apropriado (Cañigueral; Vila, 2003;Rates, 2001). Nestes termos, o emprego no atendimento primário à saúde pode gerar um impacto social (Lapa et al., 2003), com aumento de gastos nos serviços públicos de saúde, visto que as plantas com maior volume de estudos científi cos que garantam efi cácia e segurança constituem matéria-prima importada, o que torna urgente a busca de inform...

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Foeniculum vulgare therapy in irritable bowel syndrome

Cited by 3 publications

References 0 publications

Indigenous traditional medicine: in vitro anti-giardial activity of plants used in the treatment of diarrhea

Indigenous traditional medicine: in vitro anti-giardial activity of plants used in the treatment of diarrhea

Irritable bowel syndrome and diet

Dados químicos e farmacológicos sobre as plantas utilizadas como medicinais pela comunidade do bairro Ponta Grossa, Porto Alegre, Rio Grande do Sul

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