Fokale noduläre Hyperplasie und hepatozelluläres Adenom

Bastati-Huber, N.; Pötter-Lang, S.; Ba‐Ssalamah, Ahmed

doi:10.1007/s00117-014-2704-9

Cited by 4 publications

(1 citation statement)

References 32 publications

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“…Imaging features are mainly characterized by nodular hyperplasia of liver parenchyma, surrounded by central and accompanied by abnormal arteries in stellate cell fibrosis region [8,9]. Typical FNH can be imaged by CT or magnetic resonance imaging [10,11]. However, in the case of atypical FNH, the central scar reinforcement was weak or not strengthened, and the scar reinforcement was obvious, with little characteristic imaging features [12].…”

Section: Introductionmentioning

confidence: 99%

The diagnostic value of miR-21 combined with CT in patients with liver cancer

et al. 2020

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Purpose To explore the diagnostic value of miR-21 combined with computed tomography (CT) in patients with liver cancer. Methods A total of 112 patients in our hospital were confirmed liver cancer by examination, and were collected as cancer group. Another 100 patients with hepatic focal nodular hyperplasia in the same period were collected as control group. The diagnostic value of miR-21 and CT on liver cancer was observed. Results The level of miR-21 in cancer group was significantly higher than that in control group, the difference was statistically significant (p < 0.05). The alpha-fetoprotein (AFP) level was tested. It was found that the AFP level in cancer group was significantly higher than that in control group (p < 0.001). The correlation between AFP and miR-21 levels in liver cancer patients was detected. It turned out that AFP and miR-21 had correlation. According to receiver operating curve (ROC) calculation results, the best cut-off value for miR-21 diagnosis was 4.142. The sensitivity, specificity and accuracy of diagnosis of miR-21 alone were 64.29%, 87.00% and 75.00%, respectively. The sensitivity, specificity and accuracy of diagnosis of CT alone were 91.07%, 62.00% and 77.36%, respectively. There were 108 cases of true positive and 80 cases of true negative after combined diagnosis in the two groups. The sensitivity, specificity and accuracy of combined diagnosis were 96.43%, 80.00% and 88.68%, respectively. Comparing the value of single diagnosis and combined diagnosis, we found that the accuracy, sensitivity and specificity of combined diagnosis were significantly higher than that of single diagnosis (p < 0.05). Conclusion CT combined with miR-21 has great diagnostic value in liver cancer and may be a potential diagnostic indicator for liver cancer.

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