2009
DOI: 10.1016/j.ejps.2009.06.002
|View full text |Cite
|
Sign up to set email alerts
|

Folate-mediated chondroitin sulfate-Pluronic® 127 nanogels as a drug carrier

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

0
28
0

Year Published

2011
2011
2017
2017

Publication Types

Select...
8
2

Relationship

0
10

Authors

Journals

citations
Cited by 71 publications
(28 citation statements)
references
References 26 publications
0
28
0
Order By: Relevance
“…Pluronics show low cytotoxicity and weak immunogenicity after topical and systemic administration although they are not biodegradable polymers. This may be due to having molecular weight less than 15 kDa which could be easily filtered and cleared by the kidney (Huang et al, 2009). Pluronic micelles have a core-shell structure with hydrophobic core acting as solubilization depot for the non-polar drugs and hydrophilic corona preventing aggregation, protein adsorption, and recognition by the reticulo-endothelial system, which leads to longer blood circulation time.…”
Section: Introductionmentioning
confidence: 99%
“…Pluronics show low cytotoxicity and weak immunogenicity after topical and systemic administration although they are not biodegradable polymers. This may be due to having molecular weight less than 15 kDa which could be easily filtered and cleared by the kidney (Huang et al, 2009). Pluronic micelles have a core-shell structure with hydrophobic core acting as solubilization depot for the non-polar drugs and hydrophilic corona preventing aggregation, protein adsorption, and recognition by the reticulo-endothelial system, which leads to longer blood circulation time.…”
Section: Introductionmentioning
confidence: 99%
“…This character suggests that ChS is potentially a good candidate for usage as a drug carrier. [27][28][29][30] Recently, we used a method of interfacial polymerization in emulsion to fabricate chondroitin sulfatebased nanocapsules for loading of indomethacin. 31 The shell of nanocapsules consisted of the cross-linked ChS chains, and showed a much higher drug loading capacity.…”
Section: Introductionmentioning
confidence: 99%
“…This nanogel showed better cellular uptake by KB cancer cells. [123] Polycaprolactone (PCL) NPs Self-assembled PCL-g-CS NPs bearing DOX showed enhanced cell uptake in lung cancer cells. [124] Solid lipid NPs (SLNs) CS-SLNs enhanced the efficacy of aceclofenac against OA.…”
Section: Subchondral Bonementioning
confidence: 99%