Follicular Variant of Papillary Carcinoma of the Thyroid

Kumar, Perikala V.; Talei, Abdolrasoul; Malekhusseini, Seyed Ali; Monabati, Ahmad; Vasei, Mohammad

doi:10.1159/000330967

Cited by 21 publications

(34 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…INCI have been reported to a lesser extent as compared to nuclear grooves in most studies. 4,9,18 We identified INCI in 29 of 59 (49.15%) of our cases, similar to Fulciniti et al 9 and Jogai et al 20 Nuclear enlargement was a prominent finding in all our cases, and in a large proportion of the cases the nuclei were more oval than round. Like Mesonero et al, 6 we observed nuclear grooves more readily in the larger, oval nuclei as compared to the cells with small, round nuclei.…”

Section: Discussionsupporting

confidence: 89%

“…Many previous studies have stressed the importance of identifying microfollicular architecture in the diagnosis of FVPC. 6,9,17,18 However, our findings indicate that syncytial fragments may be a more common and consistent finding in FVPC than microfollicles. In the present study, the follicular pattern was absent from 11 cases, and by relying on this architectural pattern alone the diagnosis of FVPC would have been missed.…”

Section: Discussionmentioning

confidence: 48%

See 1 more Smart Citation

Fine Needle Aspiration Cytology of Follicular Variant of Papillary Carcinoma of the Thyroid

Aron

Mallik

Verma³

2006

Acta Cytologica

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 48%

Fine Needle Aspiration Cytology of Follicular Variant of Papillary Carcinoma of the Thyroid

Aron

Mallik

Verma³

2006

Acta Cytologica

View full text Add to dashboard Cite

“…Others have studied other cytologic features that might help with the differential diagnosis of FVPTC and UTPTC. Perikala et al 8 suggested that the combination of numerous colloid balls and rosettelike microfollicles is frequently seen in FVPTC and help to differentiate it from other thyroid lesions. However, in our study, although colloid balls appeared in 8 cases (67%), they were not as numerous as Perikala et al described.…”

Section: Discussionmentioning

confidence: 99%

“…This may be due to different smear and staining techniques. Perikala et al 8 used 75% ethanol for fixation and Papanicolaou stain in half their cases and used air-dried samples and Wright-Giemsa stain in the other half. All our cases were air dried and stained with Riu's stain.…”

Section: Discussionmentioning

confidence: 99%

“…6,7 Many features have been pro-posed to aid the cytologic diagnosis of FVPTC, such as colloid balls; rosettelike microfollicles; nuclear grooves; intranuclear inclusions; monolayer branched sheets; syncytial clusters; multinucleated giant cells; and ropy colloid. [7][8][9][10] In this study we investigated the diagnostic accuracy and some special features of FNAC of FVPTC.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Follicular Variant of Papillary Thyroid Carcinoma

Shih

Shun

et al. 2005

Acta Cytologica

View full text Add to dashboard Cite

Follicular Variant of Papillary Thyroid Carcinoma

Passler

Prager²,

Scheuba³

et al. 2003

Arch Surg

122

View full text Add to dashboard Cite

The clinical behavior of the follicular variant of papillary thyroid carcinoma (FVPTC) is similar to pure papillary thyroid carcinoma (PPTC) and completely different from follicular thyroid carcinoma (FTC).Design: Retrospective analysis of prospectively documented data.Setting: Referral center of a university hospital.Patients: Two hundred thirty-seven consecutive patients with follicular cell-derived thyroid carcinomas were operated on in our institution during a 15-year period, from January 1, 1980, to December 31, 1994. Of the 154 PTC patients, 37 (24%) had FVPTC. The mean follow-up was 128.2 months (10.7 years).Main Outcome Measures: Demographic features, tumor characteristics, local and distant spread, persistence or recurrence of disease, and carcinoma-related mortality were compared between the groups with FVPTC, PPTC, and non-Hü rthle cell FTC (NHFTC).Results: The frequency of multicentricity was significantly higher in the FVPTC group than in the PPTC group (P =.03) or in the NHFTC group (P =.01) (12 [32%] of 37 patients vs 17 [15%] of 117 patients vs 6 [10%] of 58 patients, respectively). The incidence of cervical lymph node metastases was lower in the FVPTC group than in the PPTC group (P = .30) and higher than in NHFTC group (P =.004) (12 [32%] of 37 patients vs 53 [45%] of 117 patients vs 6 [10%] of 58 patients, respectively). At diagnosis, no patient with FVPTC showed distant metastases, compared with 5 patients (4%) with PPTC (P=.34) and 19 (33%) with NHFTC (PϽ.001). There was no carcinoma-related death in the FVPTC group. The strikingly poorer prognosis for the NHFTC group was statistically significant (PϽ.001), whereas the difference in carcinoma-specific survival between the PPTC and the FVPTC groups did show a trend toward better survival in the FVPTC group. Conclusion:The clinical behavior of the FVPTC group did not differ significantly from that of the PPTC group, whereas compared with the NHFTC group, the FVPTC group showed statistically significant differences for most of the analyzed variables.

show abstract

Follicular Variant of Papillary Carcinoma of the Thyroid

Cited by 21 publications

References 5 publications

Fine Needle Aspiration Cytology of Follicular Variant of Papillary Carcinoma of the Thyroid

Fine Needle Aspiration Cytology of Follicular Variant of Papillary Carcinoma of the Thyroid

Follicular Variant of Papillary Thyroid Carcinoma

Follicular Variant of Papillary Thyroid Carcinoma

Contact Info

Product

Resources

About