1998
DOI: 10.1016/s0190-9622(98)70374-3
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Folliculitis spinulosa decalvans: Successful therapy with dapsone

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Cited by 40 publications
(33 citation statements)
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“…For symptomatic relief emollients, topical steroid, and keratolytic agents can be used [4]. Different systemic treatments including isotretinoin, etretinate, dapsone and antibiotics have been tried with varied results it is suggested that the use of retinoids in the early and more active phase of the disease, when histopathology shows perifollicular infiltrate, can bring some benefit [4,6,7]. Treatment is even more disappointing when the disease predominantly shows cicatricial changes, as in this present study [8].…”
Section: Discussionmentioning
confidence: 71%
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“…For symptomatic relief emollients, topical steroid, and keratolytic agents can be used [4]. Different systemic treatments including isotretinoin, etretinate, dapsone and antibiotics have been tried with varied results it is suggested that the use of retinoids in the early and more active phase of the disease, when histopathology shows perifollicular infiltrate, can bring some benefit [4,6,7]. Treatment is even more disappointing when the disease predominantly shows cicatricial changes, as in this present study [8].…”
Section: Discussionmentioning
confidence: 71%
“…There is no specific treatment for KFSD. Various drugs have been tried to delay scarring alopecia such as isotretinoin [6] and dapsone [7]. For symptomatic relief emollients, topical steroid, and keratolytic agents can be used [4].…”
Section: Discussionmentioning
confidence: 99%
“…1,4 Recently other authors have included a fourth type named folliculitis spinulosa decalvans, previously considered a persistent inflammatory variation of keratosis follicularis spinulosa decalvans 6 The term keratosis follicularis spinulosa decalvans was criated by Siemens,7 in 1926, when he described some individuals from a Bavarian family that presented follicular papules on the face, trunk and extremities with partial loss of hairs on these areas and from that moment the disease became known as Siemens syndrome. Genetic studies in Dutch and English families showed connection with the Xp21.2-p22 gene.…”
Section: Discussionmentioning
confidence: 99%
“…Genetic studies in Dutch and English families showed connection with the Xp21.2-p22 gene. 8 However, other family analyses without evidence of inheritance linked to X suggest heterogeneous transmissions 1,3,4,9 and also sporadic 6 ones. This disease starts in the early years of life, initially on the face and progressing towards the trunk and limbs and it might spread to other parts of the body.…”
Section: Discussionmentioning
confidence: 99%
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