Follow-up of children conceived from cryopreserved embryos

Health outcomes of children born after IVF/ICSI: a review of current expert opinion and literature

“…No differences in congenital malformation rates were found between children born using cryopreservation techniques and children from fresh transfer in population-based registries from Australia (Shih et al, 2008), Sweden (Källén et al, 2005) and the USA (Sassisted reproduction treatment, 1993(Sassisted reproduction treatment, , 1994(Sassisted reproduction treatment, , 1995(Sassisted reproduction treatment, , 1996(Sassisted reproduction treatment, , 1998(Sassisted reproduction treatment, , 1999(Sassisted reproduction treatment, , 2000. In three small studies including children from natural conception as controls, no differences were found in neonatal outcome or congenital malformation rate (Sutcliffe, 2000;Sutcliffe et al, 1995a;Wennerholm et al, 1998).…”

Does storage time influence postthaw survival and pregnancy outcome? An analysis of 11,768 cryopreserved human embryos

“…Human cryopreserved embryos seem to be relatively stable with no obvious deleterious time effects on pregnancy outcomes. Limited studies on obstetric outcome, as well as further follow-up of the children born, indicate that cryopreservation of embryos is a safe procedure; nevertheless, long-term follow-up of the children born is still warranted (24). Finally, no published data are available for pregnancy outcomes and long-term follow-up of embryos cryopreserved with vitrification, a promising emerging technique.…”