Follow-up of Roux-en-Y Gastric Bypass Patients at 5 or more Years Postoperatively

Pajecki, Dênis; Dalcanalle, Lorença; Oliveira, Cláudia Pinto Marques Souza de; Zilberstein, Bruno; Halpern, Alfredo; Garrido, Arthur B.; Cecconello, Ivan

doi:10.1007/s11695-007-9104-4

Cited by 81 publications

(58 citation statements)

References 35 publications

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“…In the present study, the postoperative BMI ranged from 29.4 ± 5.6 to 31.6 ± 4.3 Kg/m² and the percentage of EBWL varied from 81.7 ± 21.4% to 72.2 ± 14.2%, proportional to the postoperative period; however, no statistical differences were found among the postoperative groups. Similar find ings were obtained by SEARS et al after 1 year of RYGBP in 75 patients with BMIs of 32.3 ± 8.6, and by Pajecki et al, who followed RYGBP patients for five to nine years and observed PEP% 2 years after surgery of 80.2% (BMI 29.3 ± 6.8) that decreased to 71.81% (BMI 35.5 ± 10) 5 years after surgery (18,22) . Our findings showed a decrease in the proportion of a tendency for diabetes resolution over the long term.…”

Section: Discussionsupporting

confidence: 86%

Outcomes on Quality of Life, Weight Loss, and Comorbidities After Roux-en-Y Gastric Bypass

Costa

Yamaguchi

Santo

et al. 2014

Arq. Gastroenterol.

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Context Bariatric surgery has become the most effective method for producing weight loss in obese patients. The evaluation of improvement of comorbidities and changes in the quality of life are important outcome factors; however, it is necessary to investigate whether they persist over the long term. Methods A cross-sectional study was conducted on 143 obese patients from our institution from February 2007 to February 2008. These patients were divided into five independent groups, one being a control group, plus four other groups with 1, 2, 3, 4 or more years following surgical Roux-en-Y gastric bypass with a silicon ring banded. quality of life forms and anthropometric measurements were performed and its scores correlated with social factors, weight loss success, and status of obesity-related conditions. Results For the group that was 1 year postoperative, a significant percentage of excess body weight loss (EBWL%) of 81.7% was observed. The groups with 2, 3, 4 or more years of post-surgical follow-up showed a EBWL decline, but without significant difference. The main comorbidity percentages in all patients who had the surgery was as follows: 69.7% for hypertension; 88.2% for diabetes mellitus; and 27.5% for arthropathy. There was a significant decrease in the rate for diabetes resolution (P = 0.035) observed by evolutionary assessment of the comorbidity resolution. The results obtained by BAROS were good, very good, or excellent in more than 96% of patients in all evaluations that were performed. The use of the Moorehead-Ardelt Questionnaire (M/A) demonstrated improvement in the quality of life. Moreover, the quality of life, when evaluated through SF-36, also showed improvement in all related areas after 1 year; however, after 4 years, improvement remained elevated only in the areas of general state of health and functional capacity. Conclusions The Roux-en-Y gastric bypass procedure was able to achieve EBWL of 81.7% after 1 year following surgery, remaining steady with little decline after this period. Important resolution of comorbidities, such as hypertension and diabetes, was also seen. Immediate surgical outcomes assessed by SF-36 and M/A in the area of quality of life were satisfactory, but the general state of health and functional capacity areas were sustained satisfactory at a later time only.

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Section: Discussionsupporting

confidence: 86%

Outcomes on Quality of Life, Weight Loss, and Comorbidities After Roux-en-Y Gastric Bypass

Costa

Yamaguchi

Santo

et al. 2014

Arq. Gastroenterol.

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“…According to most studies, hypertension control appears to be so linked to improvement on insulin sensitivity and proinflammatory state as to proper weight loss (11,15,16,27) . Previous Brazilian reports have shown similar results (9,21) .…”

Section: Discussionsupporting

confidence: 78%

Control of Hypertension After Roux-en-Y Gastric Bypass Among Obese Diabetic Patients

Cazzo

Gestic

Machado

et al. 2014

Arq. Gastroenterol.

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-Context -Hypertension is a common disorder in general practice and has a widely known association with type 2 diabetes mellitus. Low adhesion to clinical treatment may lead to poor results. Obesity surgery can bring early and relevant resolution rates of both morbidities. Objective -To describe hypertension evolution after Roux-en-Y gastric bypass in patients with type 2 diabetes mellitus. Method -Descriptive observational study designed as a historical cohort of 90 subjects with hypertension and diabetes who underwent Roux-en-Y gastric bypass and were evaluated before and after surgery. Results -It was observed a hypertension resolution rate of 85.6% along with markedly decrease in anti-hypertensive usage. Mean resolution time was 3.2 months. Resolution was associated with homeostasis model assessment -insulin resistance, preoperative fasting insulin, anti-hypertensive usage, hypertension time, body mass index and percentage of weight loss. Resolution of hypertension was not statistically associated with diabetes remission within this sample. Conclusion -Roux-en-Y gastric bypass was a safe and effective therapeutic tool to achieve hypertension resolution in patients who also had diabetes mellitus.

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“…[26][27][28]47,48 Partial or complete improvement was shown within 12 months after undergoing bariatric surgery, especially among the patients who had undergone gastric bypass, 10,47 thus reducing the need for antihypertensive drugs. 49,50 It seems again that our results were somehow related to the technique used for the majority of our patients, i.e. gastric bypass.…”

Section: Antihypertensive Drugsmentioning

confidence: 77%

Medication and nutritional supplement use before and after bariatric surgery

Backes

Lopes²,

Tetelbom

et al. 2016

Sao Paulo Med. J.

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CONTEXT AND OBJECTIVE: Bariatric surgery has been an effective alternative treatment for morbid obesity and has resulted in decreased mortality, better control over comorbidities and reduced use of drugs. The objective of this study was to analyze the impact of bariatric surgery on medication drug and nutritional supplement use. DESIGN AND SETTING: Longitudinal study of before-and-after type, on 69 morbidly obese patients in a public hospital in Porto Alegre. METHODS: Through interviews, the presence of comorbidities and use of drugs with and without prescription were evaluated. RESULTS: Among the 69 patients interviewed, 85.5% had comorbidities in the preoperative period, with an average of 2.3 (± 1.5) per patient. The main comorbidities reported were hypertension, diabetes and dyslipidemia. 84.1% of the patients were using prescribed drugs in the preoperative period. The mean drug use per patient was 4.8, which decreased to 4.4 after the procedure. The surgery enabled significant reduction in use of most antidiabetic (84%), antilipemic (77%) and antihypertensive drugs (49.5%). On the other hand, there was a significant increase in use of multivitamins and drugs for disorders of the gastrointestinal tract. The dosages of most of the drugs that continued to be prescribed after surgery were decreased, but not significantly. CONCLUSION: After bariatric surgery, there were increases in the use of vitamins, gastric antisecretory drugs and antianemic drugs. Nevertheless, there was an overall reduction in drug use during this period, caused by suspension of drugs or dose reduction. RESUMO CONTEXTO E OBJETIVO:A cirurgia bariátrica tem sido uma alternativa efetiva de tratamento para a obesidade mórbida, resultando na diminuição da mortalidade, melhor controle das comorbidades e redução no uso de medicamentos. O objetivo deste estudo foi analisar o impacto da cirurgia bariátrica sobre a utilização de medicamentos e suplementos nutricionais. TIPO DE ESTUDO E LOCAL: Estudo longitudinal do tipo antes e depois com 69 pacientes obesos mórbi-dos em um hospital público de Porto Alegre. MÉTODOS: Nas entrevistas, foram avaliados a presença de comorbidades e o uso de medicamentos com e sem prescrição médica. RESULTADOS: De 69 pacientes entrevistados, 85,5% apresentaram comorbidades no período pré-cirúrgi-co, média de 2,3 (± 1,5) por paciente. As principais comorbidades relatadas foram hipertensão, diabetes e dislipidemias. 84,1% dos pacientes estavam em uso de medicamentos sob prescrição médica, no período pré-cirúrgico. A média de uso de medicamentos por paciente foi de 4,8, reduzindo para 4,4 após o procedimento. A cirurgia proporcionou diminuição significativa do uso da maioria dos antidiabéticos (84%), antilipêmicos (77%) e anti-hipertensivos (49,5%). Por outro lado, observou-se aumento significativo na utilização de multivitamínicos e medicamentos para desordens do trato gastrointestinal. A maior parte dos medicamentos que continuaram sendo prescritos após a cirurgia teve sua dose reduzida, no entanto, esta redução nã...

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Follow-up of Roux-en-Y Gastric Bypass Patients at 5 or more Years Postoperatively

Abstract: Long-term follow-up (5 to 9 years) after the RYGBP was associated with satisfactory mantainance of EWL, and resolution or improvement of the main co-morbidities was observed in the majority of the patients.

Cited by 81 publications

References 35 publications

Outcomes on Quality of Life, Weight Loss, and Comorbidities After Roux-en-Y Gastric Bypass

Outcomes on Quality of Life, Weight Loss, and Comorbidities After Roux-en-Y Gastric Bypass

Control of Hypertension After Roux-en-Y Gastric Bypass Among Obese Diabetic Patients

Medication and nutritional supplement use before and after bariatric surgery

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