Follow-Up Study of Echocardiography in 38 Children With Kawasaki Disease Complicated by Heart Lesion

Abstract

Background: The most common and most serious complication of Kawasaki disease (KD)is heart lesion(HL), which is the main cause of childhood acquired HL.Objective: Use echocardiography to study the HL recovery of children with KD complicated by HL, and provide an important theoretical basis for the prognosis of KD complicated by HL.Methods: Using prospective research methods, 38 children with KD complicated by HL were followed up for echocardiographic examination, and the longest examination time was one year. And carry on statistical analysis to the inspection data.Results: In 38 children with KD complicated by HL, 36 cases of coronary artery lesion (CAL), including 29 cases of coronary artery dilation(CAD), 7 cases of coronary artery stenosis(CAS), and 2 cases of simple pericardial effusion without CAL. CAL complicated with valve regurgitation in 4 cases, pericardial effusion in 3 cases, and left ventricular enlargement in 4 cases. In about 3 weeks, most of the pericardial effusion and mild CAD recovered. At 3 months, except for a few severe CAL, heart valve regurgitation and left ventricular enlargement all recovered. The recovery of moderate CAD was slow. One case still failed to return to normal after 1 year, but the coronary artery diameter gradually decreased.Conclusion: Kawasaki disease complicated by heart lesion mainly affects the coronary arteries, and the main manifestation is expansion. The more the expansion, the slower the recovery.