Food allergy and anaphylaxis – 2054. Easy-to-use severity grading system for treatment of symptoms induced by oral food challenge

Abstract

Easy-to-use severity grading system for treatment of symptoms induced by oral food challenge.

Development of a tool predicting severity of allergic reaction during peanut challenge

“…The CSS is novel in that it not only groups similarly severe symptoms in a more clinically meaningful way using SCI, but it incorporates the amount of food allergen ingested. 20, 51, Further, CSS provides multi-level phenotyping of clinical symptom severity on an ordinal scale that captured the allergic features of the reaction. For example, a subject who is able to consume the equivalent of one peanut (240mg) and develops limited hives would be assigned a CSS of 1, whereas a subject who can only consume a low dose of peanut (5mg) and develops wheezing would receive a CSS of 6.…”