2019
DOI: 10.1080/23744235.2018.1524582
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Foodborne botulism in Turkey, 1983 to 2017

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Cited by 10 publications
(9 citation statements)
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“…Pathophysiologically, botulinum neurotoxins, some of the most potent of all natural toxins known 6 - 8 , 15 , bind to receptors in the presynaptic membrane of neuromuscular junctions 2 , 5 leading to the irreversible blockage of exocytosis of acetylcholine in the synaptic cleft 8 , also affecting the sympathetic and parasympathetic nervous systems 2 . Thus, autonomic signs and symptoms may be present 4 , such as constipation, dry mouth, postural hypotension, pupillary alterations and urinary retention 1 , 2 , 11 .…”
Section: Discussionmentioning
confidence: 99%
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“…Pathophysiologically, botulinum neurotoxins, some of the most potent of all natural toxins known 6 - 8 , 15 , bind to receptors in the presynaptic membrane of neuromuscular junctions 2 , 5 leading to the irreversible blockage of exocytosis of acetylcholine in the synaptic cleft 8 , also affecting the sympathetic and parasympathetic nervous systems 2 . Thus, autonomic signs and symptoms may be present 4 , such as constipation, dry mouth, postural hypotension, pupillary alterations and urinary retention 1 , 2 , 11 .…”
Section: Discussionmentioning
confidence: 99%
“…The standard treatment for botulism is based on the early administration of the trivalent (A, B and E) botulinum antitoxin 13 . The antitoxin must be administrated soon after clinical suspicion of botulism made 8 , since even mouse bioassays may not confirm the diagnosis, justifying why waiting for laboratory confirmation to initiate treatment is described as a serious mistake 14 .…”
Section: Discussionmentioning
confidence: 99%
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