2019
DOI: 10.1101/627349
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FOP plays a negative role in ciliogenesis and promotes cell cycle re-entry by facilitating primary cilia disassembly

Abstract: Primary cilia are microtubule-based, antenna-like organelles, which are formed in G0 phase and resorbed as cells re-enter the cell cycle. It has been reported that the length of primary cilia can influence the timing of cell cycle progression. However, the molecular links between ciliogenesis and cell cycle progression are not clear. FOP (Fibroblast growth factor receptor 1 Oncogene Partner, also known as FGFR1OP) has been implicated in ciliogenesis. Here, we show that the expression of FOP during cell cycle e… Show more

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“…Prof. Yu Li (Harbin Institute of Technology) for providing the pEGFP-N1 vector and Kelvin K. L. Sou for technical assistance. This manuscript has been released as a pre-print at bioRxiv ( Jiang et al, 2019 ).…”
mentioning
confidence: 99%
“…Prof. Yu Li (Harbin Institute of Technology) for providing the pEGFP-N1 vector and Kelvin K. L. Sou for technical assistance. This manuscript has been released as a pre-print at bioRxiv ( Jiang et al, 2019 ).…”
mentioning
confidence: 99%