Forced Degradation Studies, Elucidation of Degradation Pathways and Degradation Kinetics of Xylopic Acid via LC and LC-MS/MS Analyses

Alolga, Raphael N.; Ayensu, Isaac; Sosu, Jerry  X.

doi:10.1016/j.xphs.2023.01.004

Search citation statements

Order By: Relevance

Paper Sections

Select...

Xylopic Acid (Xa)1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

Publication Types

Select...

Article1

Relationship

Self Cite1

Independent0

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A perusal of extant scientific literature on XA (15β-acetoxyent-kaur-16-en-19-oic acid) reveals reports on the pharmacokinetics and in vitro microsomal liver enzyme metabolism (Alolga, et al, 2023a), forced degradation studies (Alolga, et al, 2023b), quantitative analyses (Adosraku & Oppong Kyekyeku, 2011;Kyekyeku et al, 2020), semi-synthesis (Soh et al, 2022) and evaluations of diverse biological activities.…”

Section: Xylopic Acid (Xa)mentioning

confidence: 99%

Ent-kaurane diterpenoids from the Annonaceae family: a review of research progress and call for further research

Ibrahim,

Khongorzul,

Muyaba

et al. 2023

Front. Pharmacol.

Self Cite

View full text Add to dashboard Cite

The Annonaceae is one of the plant families with members that are credited with numerous pharmacological functions. Among the group of compounds responsible for these bioactivities are the ent-kaurane diterpenoids. The ent-kauranes are a group of 20-Carbon, tetracyclic diterpenoids that are widely distributed in other plant families including the Annonaceae family. This mini-review focuses mainly on the ent-kaurane diterpenoids isolated from the Annonaceae family, delineates the various biological activities of these compounds, and highlights the research gaps that exist for further scientific scrutiny.

show abstract