Compressibility effects are present in many practical turbulent flows, ranging from shockwave/boundary-layer interactions on the wings of aircraft operating in the transonic flight regime to supersonic and hypersonic engine intake flows. Besides shock wave interactions, compressible flows have additional dilatational effects and, due to the finite sound speed, pressure fluctuations are localized and modified relative to incompressible turbulent flows. Such changes can be highly significant, for example the growth rates of mixing layers and turbulent spots are reduced by factors of more than three at high Mach number. The present contribution contains a combination of review and original material. We first review some of the basic effects of compressibility on canonical turbulent flows and attempt to rationalise the differing effects of Mach number in different flows using a flow instability concept. We then turn our attention to shock-wave/boundary-layer interactions, reviewing recent progress for cases where strong interactions lead to separated flow zones and where a simplified spanwise-homogeneous problem is amenable to numerical simulation. This has led to improved understanding, in particular of the origin of low-frequency behaviour of the shock wave and shown how this is coupled to the separation bubble. Finally, we consider a class of problems including side walls that is becoming amenable to simulation. Direct effects of shock waves, due to their penetration into the outer part of the boundary layer, are observed, as well as indirect effects due to the high convective Mach number of the shock-induced separation zone. It is noted in particular how shock-induced turning of the detached shear layer results in strong localized 1 damping of turbulence kinetic energy.