Forecast of ameliorating effect of dietary flavonol consumption in white tea with or without aerobic training on type 2 diabetes (T2D) in females

pour, Elnaz Dardashti; Yaghobian, Farnaz; Dehghan, Firouzeh; Azarbayjani, Mohammad Ali

doi:10.1016/j.clnesp.2021.08.025

Cited by 7 publications

(2 citation statements)

References 54 publications

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“…White tea is an unfermented tea with various health benefits. In a randomized clinical trial, the intervention of white tea combined with physical activity improved glycemic parameters, lipid profile, blood pressure, and VO2 max (peak oxygen consumption), indicating that a healthy lifestyle that includes tea drinking and physical activity is a sustainable way to prevent and reverse T2DM. Although tea consumption is associated with a reduced risk of T2DM in general, it is important to acknowledge that the response to tea intervention may depend on each individual’s genetic factors, lifestyle, and environmental influence .…”

Section: Evidence From Epidemiological Investigationsmentioning

confidence: 99%

Antidiabetic Potential of Tea and Its Active Compounds: From Molecular Mechanism to Clinical Evidence

Wei,

Shao,

Pang

et al. 2024

J. Agric. Food Chem.

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Diabetes mellitus (DM) is a chronic endocrine disorder that poses a long-term risk to human health accompanied by serious complications. Common antidiabetic drugs are usually accompanied by side effects such as hepatotoxicity and nephrotoxicity. There is an urgent need for natural dietary alternatives for diabetic treatment. Tea (Camellia sinensis) consumption has been widely investigated to lower the risk of diabetes and its complications through restoring glucose metabolism homeostasis, safeguarding pancreatic β-cells, ameliorating insulin resistance, ameliorating oxidative stresses, inhibiting inflammatory response, and regulating intestinal microbiota. It is indispensable to develop effective strategies to improve the absorption of tea active compounds and exert combinational effects with other natural compounds to broaden its hypoglycemic potential. The advances in clinical trials and population-based investigations are also discussed. This review primarily delves into the antidiabetic potential and underlying mechanisms of tea active compounds, providing a theoretical basis for the practical application of tea and its active compounds against diabetes.

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Section: Evidence From Epidemiological Investigationsmentioning

confidence: 99%

Antidiabetic Potential of Tea and Its Active Compounds: From Molecular Mechanism to Clinical Evidence

Wei,

Shao,

Pang

et al. 2024

J. Agric. Food Chem.

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“…Konsumsi teh yang besar dikalangan masyarakat Indonesia menjadikan tanaman herbal akan divisualkan dalam bentuk teh sehingga dapat diterima oleh masyarakat dari segi bentuk dan rasa sehingga disebut dengan minuman herbal. Minuman herbal atau dalam bahasa inggris juga disebut dengan tisane menjadi sebutan untuk minuman dari ramuan bagian tanaman herbal yaitu daun, bunga, biji, akar ataupun buahnya yang dikeringkan dan perlu diketahui bahwa minuman herbal sama sekali tidak mengandung Camellia sinensis (Chandra et al, 2015).…”

Section: Pendahuluan Latar Belakangunclassified

A systematic review: Efisiensi, Mekanisme dan Keamanan Konsumsi Camellia Sinensis serta Herbal Indonesia dalam Menurunkan Resiko Obesitas

Hendryanti¹,

Josephine²,

Retnaningsih³

2023

Jurnal Sains, Teknologi, Masyarakat dan Jejaring

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Teh (Camellia sinensis) dan minuman daun herbal memiliki senyawa aktif sehingga dapat dijadikan sebagai pangan fungsional untuk mengurangi resiko yang disebabkan dari obesitas. Obesitas di Indonesia sudah menjadi salah satu masalah yang serius. Keamanan pangan tidak hanya dapat dilihat dari kenaturalan bahan tersebut. Penelitian ini dilakukan dengan metode sistematik review yang bertujuan untuk mengidentifikasi mekanisme senyawa bioaktif yang terdapat dalam teh (camellia sinensis) dan minuman daun herbal yang memiliki manfaat untuk mengurangi resiko obesitas dengan memperhatikan keamanan pangan. Hasil penelitian menunjukan teh putih, teh oolong, teh hijau, teh hitam, daun jati belanda, dan daun murbei dapat membantu menurunkan resiko obesitas karena adanya senyawa bioaktif seperti flavonoid, tanin, 1-deoxynojirimycin, kafein, katekin, dan theaflavin. Human study mengenai konsumsi teh dan minuman herbal ditemukan di semua jenis dan pada minuman herbal ditemukan pada daun Jati Belanda dan Murbei. Mekanisme yang diberikan dari senyawa bioaktif tersebut yang menurunkan resistensi insulin, mengoksidasi lemak, menurunkan kadar kolesterol, dan menekan asupan makan. Senyawa kafein dan katekin yang terdapat dalam teh dan minuman herbal bila dikonsumsi berlebih dapat memiliki efek bagi kesehatan seperti hepatitis dan hipokalemia. Kesimpulannya, teh dan daun minuman herbal memiliki manfaat pada mekanisme pencegahan resiko penurunan berat badan bila dikonsumsi dengan tepat.

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Anti-diabetic Activity of Antioxidative Teas and Tea Polyphenol Supplements

Han

Liang

Wan

et al. 2023

Dietary Supplements With Antioxidant Activity

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Diabetes, especially type 2 diabetes (T2D) mellitus, has become one of the typical chronic diseases around the world. As the most consumed beverage, tea and its main compounds, that is, tea polyphenols, have shown various regulation effects on diabetes progression. The benefits of tea and tea polyphenols on diabetes have been verified by enzyme models, cell bioassays, and animal experiments. The mechanism may be attributed to glucose hydrolysis, glucose transport, glycogen synthesis, energy expenditure, immunity regulation, and anti-inflammatory and antioxidant capacity, among others. Furthermore, population-based investigations have mostly confirmed the effects of tea on reducing diabetes risk in many epidemiological studies. However, the intervention results of tea and tea polyphenols are not consistent. The main antioxidant mechanisms of tea and tea polyphenols may involve improvement of antioxidant enzymes, inhibition of lipid peroxidation, scavenging of free radicals, and complexation of metal ions. Tea and its bioactive components offer prevention and treatment of T2D through several mechanisms, including protecting pancreatic β-cells, improving insulin resistance, inhibiting the digestion, absorption and metabolism of carbohydrates as well as regulating the gut microbiota. In addition, they also benefit diabetic complications, such as diabetic nephropathy and diabetic cardiopathy. This chapter discusses the evidence associated with the anti-diabetic activities of tea and its reactive components, as well as the underlying mechanisms that have been studied by researchers over recent years.

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Forecast of ameliorating effect of dietary flavonol consumption in white tea with or without aerobic training on type 2 diabetes (T2D) in females

Cited by 7 publications

References 54 publications

Antidiabetic Potential of Tea and Its Active Compounds: From Molecular Mechanism to Clinical Evidence

Antidiabetic Potential of Tea and Its Active Compounds: From Molecular Mechanism to Clinical Evidence

A systematic review: Efisiensi, Mekanisme dan Keamanan Konsumsi Camellia Sinensis serta Herbal Indonesia dalam Menurunkan Resiko Obesitas

Anti-diabetic Activity of Antioxidative Teas and Tea Polyphenol Supplements

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