The analysis of the current scientific and methodological principles of project management is performed. It is established that the existing models and methods cannot be used to control the configuration of integrated projects for the creation of logistics systems. The known toolkit provides general approaches to controlling the configuration of projects and does not take into account many factors of the design environment, which determine changes in the configuration of integrated projects for creating logistics systems. It has been substantiated that changes in the configuration of integrated projects for the creation of logistics systems are due to two groups of factors. They can be assessed by four criteria based on the determination of two generalized evaluative characteristics of the influence of the factors of the design environment on changes in the configuration objects of these projects. The scientific and methodological foundations of the configuration control of integrated projects for the creation of logistics systems are proposed, taking into account the changing components of their design environment. To control the configuration of integrated projects for the creation of logistics systems, the use of project management theory and system-factor principles is envisaged, which fully take into account the peculiarities of the implementation of these projects. Based on the proposed model, the impact of internal environment factors of integrated projects for the creation of logistics systems on changes in the configuration object No. 4.1 (a specialized tank truck for transporting perishable goods) was assessed. Significance coefficients are defined for each of the assigned codes (evaluation criteria and factors that determine the configuration changes) of the configuration objects of integrated projects for the creation of logistics systems. Their numerical value is in the range 0…1 and it characterizes the significance of each of the factors for a particular object of the configuration of integrated projects for the creation of logistics systems. Quantitative assessment of the impact of design environment factors on changes in the configuration of integrated projects for the creation of logistics systems is carried out on a 100-point scale.