Forensic DNA Analysis: A Powerful Investigative Tool

Kaur, Lovepreet; Sharma, Supriya

doi:10.1007/978-981-16-6683-4_1

Cited by 2 publications

(2 citation statements)

References 76 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…DNA may now be extracted, amplified, separated, and sequenced more quickly and conveniently thanks to nanotechnology (Moller & Fritzsche, 2007). In addition to revealing the physical characteristics of the owner of the DNA, such as age, sex, and the colour of the hair, eyes, and skin, among other things, next-generation sequencing using nanotechnology is also assisting the detective in determining the origin of DNA, including whether the DNA lifted from the crime scene came from skin, blood, saliva, semen, etc (Kaur & Sharma, 2022).…”

Section: Dna Analysismentioning

confidence: 99%

The Nanotechnology: An applied and extensive approach in solving crimes

Hassan

Malik

2022

IJECI

View full text Add to dashboard Cite

Nanotechnology has great influence on modern technology. In order to identify, individualize, andassess evidence, forensic science applies knowledge and methods. Then, with the aid of evidence,crime scenes will be rebuilt, investigations will be directed, and offenders will be prosecuted.Nano-analysis is one of modern technology that is most frequently used in forensic science. Thecharacterization can be done by using tools like the atomic force microscope (AFM), aman microspectroscopy, scanning electron microscope (SEM), and transmission electron microscope (TEM)(Micro-Raman). Nanotechnologies might be essential in current forensic investigation issues likeforensic toxicological analysis, explosive detection, detection of explosive residue, finger printanalysis, forensic DNA analysis, forensic nano trackers, and drug-facilitated crime.

show abstract

Section: Dna Analysismentioning

confidence: 99%

The Nanotechnology: An applied and extensive approach in solving crimes

Hassan

Malik

2022

IJECI

View full text Add to dashboard Cite

show abstract

“…Bioanalytical chemistry has played a more important role in the field of forensic research since the first introduction of DNA profiling in the 1980s [ 1 ]. The development of strategies which are rapid, low-cost, and sensitive for challenging samples will undoubtedly be the trend of future molecular forensic research [ 2 , 3 ]. And various techniques have been continuously upgraded for identifying different biological materials in forensic investigations.…”

Section: Introductionmentioning

confidence: 99%

Solving the two-decades-old murder case through joint application of ZooMS and ancient DNA approaches

Wang

Gao

et al. 2023

Int J Legal Med

View full text Add to dashboard Cite

Bones are one of the most common biological types of evidence in forensic cases. Discriminating human bones from irrelevant species is important for the identification of victims; however, the highly degraded bones could be undiagnostic morphologically and difficult to analyze with standard DNA profiling approaches. The same challenge also exists in archaeological studies. Here, we present an initial study of an analytical strategy that involves zooarchaeology by mass spectrometry (ZooMS) and ancient DNA methods. Through the combined strategy, we managed to identify the only biological evidence of a two-decades-old murder case — a small piece of human bone out of 19 bone fragments — and confirmed the kinship between the victim and the putative parents through joint application of next-generation sequencing (NGS) and Sanger sequencing methods. ZooMS effectively screened out the target human bone while ancient DNA methods improve the DNA yields. The combined strategy in this case outperforms the standard DNA profiling approach with shorter time, less cost, as well as higher reliability for the genetic identification results. Highlights • The first application of zooarchaeology by mass spectrometry technique in the forensic case for screening out human bones from bone fragment mixtures. • Application of ancient DNA technique to recover the highly degraded DNA sequence from the challenging sample that failed standard DNA profiling approaches. • A fast, sensitive, and low-cost strategy that combines the strengths of protein analysis and DNA analysis for kinship identification in forensic research.

show abstract

Forensic DNA Analysis: A Powerful Investigative Tool

Cited by 2 publications

References 76 publications

The Nanotechnology: An applied and extensive approach in solving crimes

The Nanotechnology: An applied and extensive approach in solving crimes

Solving the two-decades-old murder case through joint application of ZooMS and ancient DNA approaches

Contact Info

Product

Resources

About