Forensic effectiveness and population differentiations study of AGCU 21 + 1 fluorescence multiplex in Chinese Henan Han population

Shen, Chunmei; Wang, Hongdan; Feng, Zhanqi; Dong, Qi; Guo, Yuxin; Wang, Xinxin; Meng, Hao-Tian; Ma, Ruilin; Yan, Jiangwei; Zhu, Bofeng; Tai, Fadao

doi:10.1016/j.fsigen.2017.01.013

Cited by 6 publications

(3 citation statements)

References 23 publications

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“…The results of Figure 3, 4 and 5 showed that the Henan Han was clustered with the groups from East Asian like Shanghai Han, Northern Han, Singapore Han, Shaanxi Han, etc. which were in accordance with many previous studies on different genetic markers, such as the population genetic analysis based on the 21 or 20 STRs of Chinese Henan Han, respectively [38,39].…”

Section: Discussionsupporting

confidence: 92%

Genetic polymorphisms and association of KIR-HLA system of Chinese Henan Han population and an extensive KIR gene diversity study between populations distributed worldwide

Wang¹,

Feng²,

Guo³

et al. 2018

Oncotarget

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Section: Discussionsupporting

confidence: 92%

Genetic polymorphisms and association of KIR-HLA system of Chinese Henan Han population and an extensive KIR gene diversity study between populations distributed worldwide

Wang¹,

Feng²,

Guo³

et al. 2018

Oncotarget

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“…Linkage disequilibrium (LD) tests between all pairs of STR loci were performed using Arlequin v3.5.2 software (Excoffier & Lischer, ). To measure interpopulation differentiation, pairwise F ST values and corresponding p ‐values were calculated by analysis of molecular variance (AMOVA) using Arlequin v3.5.2 software between the Shanghai_Han population and 23 other populations in mainland China for which data were available, including the Liaoning_Han (Xiao, Yu, & Zhou, ), Shandong_Han (Han et al, ), Henan_Han (Shen et al, ), Guanzhong_Han (Zhang, Tang, et al, ), Ningxia_Han (Wang, Liao, et al, ), Hunan_Han (Guo et al, ), Chengdu_Han (Li et al, ), Guangdong_Han (Lu, Qiu, Liu, Du, & Chen, ), Hainan_Han (Guo, Wang, Liu, Liu, & Deng, ), Xinjiang_Kazak (Yuan, Wang, et al, ), Xinjiang_Kyrgyz (Guo et al, ), Xinjiang_Uygur (Guo et al, ), Xinjiang_Xibe (Meng et al, ), Inner Mongolian_Russian (Wang, Shen, et al, ), Mongolian (Gao et al, ), Gansu_Yugu (Zhang, Ma, Sun, Yang, & Luo, ), Gansu_Tibetan (Zang et al, ), Qinghai_Salar (Teng et al, ), Hubei_Tujia (Yuan et al, ), Fujian_She (Yuan, Ou, et al, ), Yunnan_Bai (Shen et al, ), Yunnan_Yi (Zhu et al, ), and Hainan_Li (Guo, Guo, et al, ) populations. SPSS 24 software (IBM Corp, ) was used to create a multidimensional scaling (MDS) plot on the basis of pairwise overall F ST values.…”

Section: Methodsmentioning

confidence: 99%

RETRACTED: Genetic polymorphism and phylogenetic analyses of 21 non‐CODIS STR loci in a Chinese Han population from Shanghai

Zhou

Shao

Xie

et al. 2019

Molec Gen & Gen Med

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Background: Short tandem repeats (STRs) are essential genetic markers for forensic applications and population estimations; thus the population genetics of STR loci have been extensively studied and discussed. Methods: In the present study, we detected 21 autosomal noncombined DNA index system (non-CODIS) STR loci in a Chinese Han population from Shanghai, calculated their forensic parameters and analyzed their genetic relationships with reported reference populations in mainland China. Results: A total of 173 alleles were observed, with corresponding allele frequencies from 0.0020 to 0.5512. The cumulative power of discrimination (CPD) and the cumulative probability of exclusion (CPE) values of the 21 STR loci were 0.99999999 9999999999997337058271 and 0.99999953732495, respectively. The results of interpopulation differentiation, phylogenetic, multidimensional scaling, and structure analyses indicated a closer genetic relationship of the studied population with Han populations from other regions of China than with other populations. Conclusions: The 21 STR loci exhibited high genetic polymorphism in the studied Shanghai_Han population and could be used for forensic applications and population genetic studies. K E Y W O R D S AGCU EX21+1, Chinese Han population, forensic genetics, population genetics, STR

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“…In the past decades, comprehensive recognition of human STRs has provided insights into anthropology, archaeology, human forensics and population genetics 4 , 5 . Recently, non-Combined DNA Index System short tandem repeats (non-CODIS STRs) are attractive to genetic applications like population stratification analysis, regional population structure studies and forensic individual identification and paternity testing 6 – 12 . Non-CODIS STRs combined with previous commercial CODIS STRs amplification systems play an indispensable complementary role in the forensic applications: disentangling missing person cases, identifying victims, and solving the parentage testing cases with mutation.…”

Section: Introductionmentioning

confidence: 99%

Genetic diversity and phylogenetic characteristics of Chinese Tibetan and Yi minority ethnic groups revealed by non-CODIS STR markers

Wang

Zou

et al. 2018

Sci Rep

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Non-CODIS STRs, with high polymorphism and allele frequency difference among ethnically and geographically different populations, play a crucial role in population genetics, molecular anthropology, and human forensics. In this work, 332 unrelated individuals from Sichuan Province (237 Tibetan individuals and 95 Yi individuals) are firstly genotyped with 21 non-CODIS autosomal STRs, and phylogenetic relationships with 26 previously investigated populations (9,444 individuals) are subsequently explored. In the Sichuan Tibetan and Yi, the combined power of discrimination (CPD) values are 0.9999999999999999999 and 0.9999999999999999993, and the combined power of exclusion (CPE) values are 0. 999997 and 0.999999, respectively. Analysis of molecular variance (AMOVA), principal component analysis (PCA), multidimensional scaling plots (MDS) and phylogenetic analysis demonstrated that Sichuan Tibetan has a close genetic relationship with Tibet Tibetan, and Sichuan Yi has a genetic affinity with Yunnan Bai group. Furthermore, significant genetic differences have widely existed between Chinese minorities (most prominently for Tibetan and Kazakh) and Han groups, but no population stratifications rather a homogenous group among Han populations distributed in Northern and Southern China are observed. Aforementioned results suggested that these 21 STRs are highly polymorphic and informative in the Sichuan Tibetan and Yi, which are suitable for population genetics and forensic applications.

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Forensic effectiveness and population differentiations study of AGCU 21 + 1 fluorescence multiplex in Chinese Henan Han population

Cited by 6 publications

References 23 publications

Genetic polymorphisms and association of KIR-HLA system of Chinese Henan Han population and an extensive KIR gene diversity study between populations distributed worldwide

Genetic polymorphisms and association of KIR-HLA system of Chinese Henan Han population and an extensive KIR gene diversity study between populations distributed worldwide

RETRACTED: Genetic polymorphism and phylogenetic analyses of 21 non‐CODIS STR loci in a Chinese Han population from Shanghai

Genetic diversity and phylogenetic characteristics of Chinese Tibetan and Yi minority ethnic groups revealed by non-CODIS STR markers

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