Forensic-paternity effectiveness and genetics population analysis of six non-CODIS mini-STR loci (D1S1656, D2S441, D6S1043, D10S1248, D12S391, D22S1045) and SE33 in Mestizo and Amerindian populations from Mexico

Burguete-Argueta, Nelsi; Cruz, Braulio Martínez De la; Camacho-Mejorado, Rafael; Santana, Carla; Noris, Gino; López-Bayghen, Esther; Arellano‐Galindo, José; Majluf‐Cruz, Abraham; Meraz-Ríos, Marco Antonio; Gómez, Rocío

doi:10.3109/03014460.2015.1127424

Cited by 5 publications

(5 citation statements)

References 33 publications

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“…GC samples were obtained from the Central Valley of Mexico (including the states of Guanajuato, Mexico City, Puebla and Queretaro) places of birth reported by CMA and healthy subjects. Of note, each one of the GC subjects has a genetic profile analysis with 21 neutral polymorphisms belonging to the combined DNA index system, guaranteeing that there was no genetic relationship among the individuals included [37,38]. The differences between GC and the healthy group are that in the latter, the atherothrombotic status is known and exhibits homogeneity about their CVDs physiological condition (disease absence).…”

Section: Characteristics Of the Studied Groupsmentioning

confidence: 99%

ALOX5,LPA,MMP9andTPOgene polymorphisms increase atherothrombosis susceptibility in middle-aged Mexicans

et al. 2020

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Atherothrombosis is the cornerstone of cardiovascular diseases and the primary cause of death worldwide. Genetic contribution to disturbances in lipid metabolism, coagulation, inflammation and oxidative stress increase the susceptibility to its development and progression. Given its multifactorial nature, the multiloci studies have been proposed as potential predictors of susceptibility. A cross-sectional study was conducted to explore the contribution of nine genes involved in oxidative stress, inflammatory and thrombotic processes in 204 subjects with atherothrombosis matched by age and gender with a healthy group ( n = 204). To evaluate the possibility of spurious associations owing to the Mexican population genetic heterogeneity as well as its ancestral origins, 300 unrelated mestizo individuals and 329 Native Americans were also included. ALOX5 , LPA , MMP9 and TPO gene polymorphisms, as well as their multiallelic combinations, were twice to four times more frequent in those individuals with clinical manifestations of atherothrombosis than in the healthy group. Once adjusting for population stratification was done, these differences remained. Our results add further evidence on the contribution of ALOX5 , LPA , MMP9 and TPO polymorphisms to atherothrombosis development in the middle-aged group, emphasizing the multiethnic studies in search of gene risk polymorphisms.

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Section: Characteristics Of the Studied Groupsmentioning

confidence: 99%

ALOX5,LPA,MMP9andTPOgene polymorphisms increase atherothrombosis susceptibility in middle-aged Mexicans

et al. 2020

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“…Thus, the establishment of parentage, by the current tests such as ABO, HLA, MNS, Kell, is a real problem, with low exclusion probabilities in the order of 0.17 [4]. Taking these limitations into account, in the context of paternity research, it is necessary to combine several systems [ABO, rhesus, HLA, MNS, Kell, serum systems...] or to use other more e cient systems such as microsatellite genetic analysis, or "short tandem repeats" (STR) [5,6].…”

Section: Introductionmentioning

confidence: 99%

“…[10]. They have a wide diversity and can be used in the identi cation of paternity testing cases [6,11]. The application of STRs to the search for parentage in 877 paternity cases had in the past ruled out 35.2% of cases and found a probability of paternity of 99.9999% [12].…”

Section: Introductionmentioning

confidence: 99%

Contribution of ABO-Rhesus/Electrophoresis of hemoglobin methods and Short Tandem Repeats analysis in the determination of paternity in Burkina Faso, West Africa

Millogo¹,

Soubeïga²,

BAZIE³

et al. 2020

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Background: the establishment of filiation by the current ABO, HLA, MNS, Kells and serum tests, pose a real reliability problem. It is then necessary to combine these methods with or to use high-performance methods such as microsatellite genetic analysis or short tandem repeats. This study aimed to compare the short tandem repeat technique with ABO/Rhesus system in combination with electrophoresis of hemoglobin. Methods: Fourteen (14) contested paternity trios were investigated. Blood samples were collected to determine blood groups using the Beth-Vincent method and the type of hemoglobin by electrophoresis. Blood spots on FTA paper were used for the analysis of 16 STR loci (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818, FGA, Amel) by capillary electrophoresis on the ABI 31310 Genetic Analyzer. The generated sequences were analyzed with GeneMapper® software version 3.2.1. The data were analyzed to determine the paternity index and the probability of paternity. Results: Of the fourteen (14) trios studied, ten (10) cases were probable inclusion, three (03) cases were exclusion and one (01) case was an undetermined paternity outcome with the ABO-Rhesus/ electrophoresis of hemoglobin system. While the analysis of genetic polymorphisms in DNA gave five (05) inclusions versus nine (09) exclusions of paternity. Of the 10 probable inclusion cases given by the ABO-Rhesus/Electrophoresis of hemoglobin system, only 05 cases (50%) were confirmed for inclusion by Short tandem repeat analysis. Conclusion: The analysis of short tandem repeat with sixteen genetic markers is more reliable in determining paternity than ABO-Rhesus/hemoglobin electrophoresis techniques.

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“…limited when there is correspondence between the Hb genotype of the alleged father-mother and child. Taking these limitations into account, in the context of paternity research, it is necessary to combine several systems [ABO, rhesus, HLA, MNS, Kell, serum systems...] or to use other more efficient systems such as microsatellite genetic analysis, or "short tandem repeats" (STR) [7,8]. Hemoglobin electrophoresis is complementary to ABOrhesus because the first is for "exclusion" when the latter detected "inclusion".…”

mentioning

confidence: 99%

“…[12]. They present a wide diversity and can be used in the identification of paternity testing cases [8,13]. The application of STRs to the search for parentage in 877 paternity cases had in the past ruled out 35.2% of cases and found a probability of paternity of 99.9999% [14].…”

mentioning

confidence: 99%

Disputed paternity presumption in Burkina Faso: determination of the biological fathers of children using ABO-rhesus/hemoglobin electrophoresis and STR assays

Millogo

Soubeïga

BAZIE

et al. 2021

Journal of Genetic Engineering and Biotechnology

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Background In resource-limited countries, ABO, HLA, MNS, Kells, and hemoglobin electrophoresis are classic tests for the resolution of paternity disputes due to their affordable cost. The limitations of these tests in cases of disputed paternity require the use of Short Tandem Repeats (STR) for their certification. This study aimed to determine the biological fathers of children using ABO-rhesus/hemoglobin electrophoresis and STR assays in Burkina Faso, West Africa. Results Of the fourteen trios studied, the ABO-rhesus/hemoglobin electrophoresis analysis revealed ten probable inclusion cases, three exclusion cases, and one undetermined paternity. DNA STR analysis found five inclusions of paternity out of the ten probable inclusions with ABO-rhesus/hemoglobin electrophoresis assay versus nine exclusions of paternity. Conclusion This study showed that the implementation of the analysis of short tandem repeat is required to resolve increasing disputed filiation cases in Burkina Faso.

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Forensic-paternity effectiveness and genetics population analysis of six non-CODIS mini-STR loci (D1S1656, D2S441, D6S1043, D10S1248, D12S391, D22S1045) and SE33 in Mestizo and Amerindian populations from Mexico

Cited by 5 publications

References 33 publications

ALOX5,LPA,MMP9andTPOgene polymorphisms increase atherothrombosis susceptibility in middle-aged Mexicans

ALOX5,LPA,MMP9andTPOgene polymorphisms increase atherothrombosis susceptibility in middle-aged Mexicans

Contribution of ABO-Rhesus/Electrophoresis of hemoglobin methods and Short Tandem Repeats analysis in the determination of paternity in Burkina Faso, West Africa

Disputed paternity presumption in Burkina Faso: determination of the biological fathers of children using ABO-rhesus/hemoglobin electrophoresis and STR assays

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